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Study breakdown

Adults who both vape and smoke cannabis had the most behavioral health problems

Cross SectionalModerate evidence
The takeaway

Among 7,178 adult cannabis users, those who both vaped and smoked (dual-use, 20%) had nearly twice the odds of severe externalizing symptoms compared to smoking-only users, while vaping-only users were more likely to be White and higher income.

Addiction clinicians, mental health providers, cannabis researchers

Dual cannabis vaping/smoking users had 1.89x higher odds of severe externalizing symptoms

What the researchers found

Dual-use (20% of users) associated with severe externalizing symptoms (OR 1.89); vaping-only (9.1%) associated with White race (OR 3.90) and higher income (OR 2.56) vs smoking-only; over 56% smoked only.

Why it matters

Cannabis consumption methods are shifting, and the finding that dual-use carries the highest behavioral health burden suggests this group needs targeted clinical attention.

The numbers in context

7,178 cannabis users; 56% smoke only; 9.1% vape only; 20% dual-use; dual-use severe externalizing OR=1.89; vape-only: White OR=3.90, higher income OR=2.56.

How the study worked

Cross-sectional analysis of PATH Study Wave 6; 7,178 adult current cannabis users classified by method (smoking only, vaping only, dual-use, other); multinomial logistic regression for sociodemographic and mental health correlates.

What this study cannot tell us

Cross-sectional PATH data; self-reported methods and mental health; cannot determine direction of association; "other methods" category is heterogeneous.

How to read the evidence

Nationally representative PATH data with clear method-specific profiles, but cross-sectional design prevents causal interpretation.

When this study was published

Published 2025

The bigger picture

The demographic and mental health profiles differ substantially by cannabis consumption method, challenging one-size-fits-all approaches to cannabis-related clinical care.

Questions still open

  • Do externalizing symptoms drive dual-use or vice versa? Why is vaping-only associated with higher socioeconomic status? Does dual-use involve higher total THC exposure?

Common questions

Does how you use cannabis matter for mental health?
Yes. Adults who both vaped and smoked cannabis had nearly twice the odds of severe externalizing symptoms (aggression, attention problems) compared to those who only smoked.
Who vapes cannabis?
Vaping-only cannabis users were nearly 4x more likely to be White and 2.5x more likely to have higher incomes compared to smoking-only users.

Read the original research

Examining the Relationship of Cannabis use Patterns, Mental Health, and Sociodemographic Factors: A Focus on Cannabis Vaping, Smoking and Dual-Use.

Addictive behaviors, 163, 108263

Citation

Chung, Jack Y C; Lim, Carmen C W; Connor, Jason P; Hall, Wayne; Stjepanović, Daniel; Chan, Gary C K. (2025). Examining the Relationship of Cannabis use Patterns, Mental Health, and Sociodemographic Factors: A Focus on Cannabis Vaping, Smoking and Dual-Use.. Addictive behaviors, 163, 108263. https://doi.org/10.1016/j.addbeh.2025.108263

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