Cannabis use in teens signals mental health risk, but mostly because of other factors

Among over 10,000 secondary school students, cannabis use was linked to mental health problems, but the association was largely explained by other risk factors like truancy, alcohol use, and adverse life events.

van Gastel, W A et al.·Psychological medicine·2013·Moderate EvidenceCross-Sectional
RTHC-00745Cross SectionalModerate Evidence2013RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=10,324

What This Study Found

In a survey of 10,324 secondary school students aged 11 to 16, past-month cannabis use was associated with a 4.5-fold increase in the odds of clinically relevant mental health problems as measured by the Strengths and Difficulties Questionnaire. However, when researchers adjusted for a comprehensive list of other risk factors, cannabis was no longer significantly associated with poor mental health.

The risk factors that explained the association included low educational track, alcohol use, cigarette smoking, hard drug use, frequent truancy, unfavorable school evaluation, feeling unsafe at school, victimization, frequent illness-related absence, having a mentally ill parent, parental abuse, financial problems, and distress from adverse events. Many of these factors were also independently associated with cannabis use itself.

Key Numbers

Among 10,324 students (ages 11-16), past-month cannabis use had an unadjusted odds ratio of 4.46 (95% CI: 3.46-5.76) for clinically relevant SDQ scores. After adjusting for all other risk factors, the association was no longer statistically significant.

How They Did This

Cross-sectional survey of 10,324 students aged 11-16 participating in a Public Health Service School Survey in the Netherlands. Students reported on demographics, substance use, school factors, and stressful life events and completed the Strengths and Difficulties Questionnaire. Logistic regression models examined the cannabis-mental health association before and after adjusting for other risk factors.

Why This Research Matters

This study reframes cannabis use in adolescence not as a direct cause of mental health problems but as an indicator or marker that a young person may be experiencing multiple risk factors simultaneously. This distinction matters for how schools and public health systems approach prevention.

The Bigger Picture

The finding that cannabis use functions as a risk indicator rather than an independent cause aligns with research showing that adolescent substance use typically clusters with other behavioral and environmental risk factors. Interventions focused solely on cannabis prevention may miss the broader picture.

What This Study Doesn't Tell Us

Cross-sectional design cannot determine temporal ordering or causation. Self-reported data may be subject to underreporting, especially for substance use. The study was conducted in the Netherlands, where cannabis policies differ from many other countries. A trend-level association remained after full adjustment, suggesting cannabis may still play some role.

Questions This Raises

  • ?Does cannabis use contribute to mental health risk beyond what confounders explain, or is it purely an indicator?
  • ?Would longitudinal tracking show cannabis use preceding the development of mental health problems in some cases?
  • ?Do these findings hold in countries with different cannabis policy environments?

Trust & Context

Key Stat:
4.5x higher odds of mental health problems with cannabis use, but not after adjusting for other factors
Evidence Grade:
Large population-based sample with comprehensive adjustment for confounders, though cross-sectional design limits causal conclusions.
Study Age:
Published in 2013. The debate about cannabis as cause vs. indicator of adolescent mental health risk continues.
Original Title:
Cannabis use as an indicator of risk for mental health problems in adolescents: a population-based study at secondary schools.
Published In:
Psychological medicine, 43(9), 1849-56 (2013)
Database ID:
RTHC-00745

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does teen cannabis use cause mental health problems?

This study found that the association between teen cannabis use and mental health problems was largely explained by other risk factors like truancy, alcohol use, and adverse experiences. Cannabis use appeared to function more as an indicator of risk than an independent cause.

What other factors explained the link between cannabis and mental health in teens?

Key confounders included alcohol and cigarette use, hard drug use, frequent truancy, feeling unsafe at school, being victimized, having a mentally ill parent, and experiencing parental abuse or financial problems.

Read More on RethinkTHC

Cite This Study

RTHC-00745·https://rethinkthc.com/research/RTHC-00745

APA

van Gastel, W A; Tempelaar, W; Bun, C; Schubart, C D; Kahn, R S; Plevier, C; Boks, M P M. (2013). Cannabis use as an indicator of risk for mental health problems in adolescents: a population-based study at secondary schools.. Psychological medicine, 43(9), 1849-56. https://doi.org/10.1017/S0033291712002723

MLA

van Gastel, W A, et al. "Cannabis use as an indicator of risk for mental health problems in adolescents: a population-based study at secondary schools.." Psychological medicine, 2013. https://doi.org/10.1017/S0033291712002723

RethinkTHC

RethinkTHC Research Database. "Cannabis use as an indicator of risk for mental health probl..." RTHC-00745. Retrieved from https://rethinkthc.com/research/van-2013-cannabis-use-as-an

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.