E-Cigarette Use Predicted Starting Marijuana Among Hispanic Young Adults Who Had Not Previously Used It

Among Hispanic young adults who were not using marijuana in 2014, those who used e-cigarettes were nearly twice as likely to be using marijuana one year later compared to non-e-cigarette users.

Unger, Jennifer B et al.·Drug and alcohol dependence·2016·Moderate EvidenceLongitudinal Cohort
RTHC-01287Longitudinal CohortModerate Evidence2016RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Longitudinal Cohort
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Researchers followed 1,332 Hispanic young adults in Los Angeles over one year. Among those who were not using marijuana in 2014, e-cigarette users were nearly twice as likely to be using marijuana by 2015 (24% vs 12%, OR = 1.97).

The effect was even stronger for cigarette smoking: among non-smokers, e-cigarette users were over 3 times more likely to become smokers (26% vs 7%, OR = 3.32).

Importantly, among people who were already using marijuana or cigarettes, e-cigarette use was not associated with changes in use of either substance. E-cigarette use was also not associated with smoking cessation among current smokers.

This pattern suggests e-cigarettes may serve as a gateway to other substances for non-users but do not increase use among existing users or help smokers quit.

Key Numbers

1,332 Hispanic young adults. Past-month prevalence in 2014: e-cigarettes 9%, cigarettes 21%, marijuana 23%. Among marijuana non-users, e-cigarette users had 1.97x odds of starting marijuana. Among non-smokers, e-cigarette users had 3.32x odds of starting cigarettes.

How They Did This

Longitudinal survey study of 1,332 Hispanic young adults (59% female, mean age 22.7) in Los Angeles, California. Data collected in 2014 and 2015. Logistic regression examined whether e-cigarette use in 2014 predicted cigarette and marijuana use in 2015, controlling for age, sex, and other substance use.

Why This Research Matters

This is one of the first longitudinal studies to show that e-cigarette use predicts subsequent marijuana initiation, not just tobacco. The finding in a Hispanic young adult population is particularly important given disparities in substance use prevention and treatment access.

The Bigger Picture

The "gateway" debate has historically focused on marijuana leading to harder drugs. This study suggests the gateway concept may need updating: e-cigarettes may serve as a gateway to both tobacco and marijuana, potentially lowering the barrier to inhaling substances for young people who might not have otherwise tried them.

What This Study Doesn't Tell Us

Observational design cannot prove e-cigarettes caused subsequent substance initiation. Unmeasured confounders (risk-taking personality, peer environment) could explain the association. The sample was entirely Hispanic young adults in Los Angeles, limiting generalizability. Two time points one year apart may miss important temporal patterns.

Questions This Raises

  • ?Does the e-cigarette to marijuana pathway hold in other demographic groups?
  • ?Is the association driven by shared social contexts or by nicotine exposure changing brain reward sensitivity?
  • ?Would restricting e-cigarette access reduce marijuana initiation rates?

Trust & Context

Key Stat:
E-cigarette users were 1.97x more likely to start marijuana and 3.32x more likely to start cigarettes within one year.
Evidence Grade:
Moderate evidence from a prospective longitudinal study with appropriate controls, though limited by the observational design and single demographic group.
Study Age:
Published in 2016. The e-cigarette landscape has changed dramatically since, with newer device types potentially altering these patterns.
Original Title:
E-cigarette use and subsequent cigarette and marijuana use among Hispanic young adults.
Published In:
Drug and alcohol dependence, 163, 261-4 (2016)
Database ID:
RTHC-01287

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Follows a group of people over time to track how outcomes develop.

What do these levels mean? →

Frequently Asked Questions

Do e-cigarettes lead to marijuana use?

This study found that e-cigarette users were nearly twice as likely to start using marijuana within a year. However, this is an association, not proof of causation. It may be that people inclined to try new substances are drawn to both e-cigarettes and marijuana.

Do e-cigarettes help people quit smoking?

In this study, e-cigarette use among current smokers was not associated with smoking cessation one year later. Among non-smokers, e-cigarette use actually predicted starting cigarettes, suggesting a net negative public health effect in this population.

Read More on RethinkTHC

Cite This Study

RTHC-01287·https://rethinkthc.com/research/RTHC-01287

APA

Unger, Jennifer B; Soto, Daniel W; Leventhal, Adam. (2016). E-cigarette use and subsequent cigarette and marijuana use among Hispanic young adults.. Drug and alcohol dependence, 163, 261-4. https://doi.org/10.1016/j.drugalcdep.2016.04.027

MLA

Unger, Jennifer B, et al. "E-cigarette use and subsequent cigarette and marijuana use among Hispanic young adults.." Drug and alcohol dependence, 2016. https://doi.org/10.1016/j.drugalcdep.2016.04.027

RethinkTHC

RethinkTHC Research Database. "E-cigarette use and subsequent cigarette and marijuana use a..." RTHC-01287. Retrieved from https://rethinkthc.com/research/unger-2016-ecigarette-use-and-subsequent

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.