CBD Labels Made Cannabis Seem Safer but Less Worth Buying Compared to THC Labels

In an experiment with 431 cannabis users, CBD-dominant product labels were perceived as least harmful and most beneficial but least likely to be purchased, while visual potency aids did not change perceptions.

Stanz, Joshua L et al.·Annals of behavioral medicine : a publication of the Society of Behavioral Medicine·2025·Moderate Evidenceclinical-trial
RTHC-07716Clinical TrialModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
clinical-trial
Evidence
Moderate Evidence
Sample
N=431

What This Study Found

CBD-dominant products were rated least harmful, most beneficial, and least likely to purchase or use compared to THC-dominant or equal-ratio products. Adding visual aids to communicate potency did not significantly change any perceptions (all Ps>0.10). Perceived benefits mediated the relationship between cannabinoid content and likelihood to use, but perceived harms did not.

Key Numbers

431 participants. CBD-dominant: least harmful, most beneficial, least likely to purchase. THC-dominant: most likely to purchase. Visual aids: no significant effect (all P>0.10). Benefits mediated use likelihood (b=-0.14). Harms did not mediate (b=-0.01).

How They Did This

3x2 mixed experimental design: within-subjects cannabinoid content (THC-dominant, CBD-dominant, 1:1) by between-subjects display type (numeric vs. numeric + visual aid). 431 cannabis users recruited via Prolific.com evaluated product packages online.

Why This Research Matters

As cannabis labeling regulations develop, understanding how label information influences consumer behavior is critical. The finding that benefit perceptions drive use decisions more than harm perceptions has implications for label design and health communication.

The Bigger Picture

The paradox that CBD products are perceived as most beneficial yet least desired for purchase suggests consumers may value the psychoactive effects of THC over the perceived health benefits of CBD. Label design alone may have limited influence on use behavior.

What This Study Doesn't Tell Us

Online experiment with hypothetical purchase decisions. Cannabis users only, not the general population. Cannot assess actual purchasing behavior. Product labels were simplified experimental stimuli. Prolific sample may not represent all cannabis consumers.

Questions This Raises

  • ?Would real-world purchase data confirm these label effects?
  • ?Could health warning labels on THC products reduce use willingness?

Trust & Context

Key Stat:
Evidence Grade:
Controlled experimental design with adequate sample, but hypothetical online decisions and cannabis-user-only sample limit to moderate.
Study Age:
Recent experimental study.
Original Title:
Cannabinoid content on product labels influences cannabis health perceptions.
Published In:
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 59(1) (2025)
Database ID:
RTHC-07716

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

Do cannabis labels change what people buy?

The cannabinoid content listed on labels influenced how healthy people perceived products, but THC-dominant products were still most desired for purchase despite being seen as more harmful.

Do visual potency indicators help?

No. Adding visual aids to show cannabinoid potency did not change how people perceived the products' health effects or their willingness to buy them.

Read More on RethinkTHC

Cite This Study

RTHC-07716·https://rethinkthc.com/research/RTHC-07716

APA

Stanz, Joshua L; Ladd, Benjamin O; Magnan, Renee E. (2025). Cannabinoid content on product labels influences cannabis health perceptions.. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 59(1). https://doi.org/10.1093/abm/kaaf046

MLA

Stanz, Joshua L, et al. "Cannabinoid content on product labels influences cannabis health perceptions.." Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2025. https://doi.org/10.1093/abm/kaaf046

RethinkTHC

RethinkTHC Research Database. "Cannabinoid content on product labels influences cannabis he..." RTHC-07716. Retrieved from https://rethinkthc.com/research/stanz-2025-cannabinoid-content-on-product

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.