Only 21% of Pregnant Women Received Guideline-Adherent Cannabis Counseling at Prenatal Visits

Across 9 US states, only about 21% of pregnant women received cannabis advice consistent with clinical guidelines, though screening was more common in states with recreational legalization.

Skelton, Kara R et al.·Drug and alcohol dependence reports·2025·Moderate EvidenceObservational
RTHC-07674ObservationalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Moderate Evidence
Sample
N=742,491

What This Study Found

Only 20.53% received guideline-adherent cannabis advice. Women in recreational legalization states were more often asked about cannabis (78.66% vs. 62.30%, p<0.001) and advised against use during pregnancy (44.29% vs. 37.06%, p<0.001) and lactation (31.03% vs. 25.50%, p<0.001). Notably, women who used cannabis prenatally were more likely to report being advised to use it (10.10% vs. 1.16%, p<0.001).

Key Numbers

Weighted N=742,491 across 9 states. 20.53% received guideline-adherent advice. RCL states: 78.66% asked about cannabis vs. 62.30% without RCL. 2.96% in RCL states advised to use cannabis vs. 1.45% without. 10.10% of prenatal cannabis users were advised to use vs. 1.16% of non-users.

How They Did This

Repeated cross-sectional study using 2017-2020 Pregnancy Risk Assessment Monitoring System (PRAMS) data from 9 US states (weighted N=742,491). Examined cannabis screening and advice at prenatal visits, adherence to ACOG guidelines, and variation by recreational legalization status.

Why This Research Matters

With prenatal cannabis use rising alongside legalization, consistent clinical guidance is critical. This study reveals that the majority of pregnant women do not receive guideline-adherent cannabis counseling, regardless of state legalization status.

The Bigger Picture

The finding that some women are being advised to use cannabis during pregnancy, and that this is more common among those already using it, suggests a troubling gap between clinical guidelines and practice. This is especially concerning given limited safety data for prenatal cannabis exposure.

What This Study Doesn't Tell Us

Self-reported screening and advice may be subject to recall bias. Only 9 states included, limiting generalizability. Cannot determine quality or depth of counseling conversations. State-level legalization status may not capture local availability.

Questions This Raises

  • ?Why are some prenatal providers advising cannabis use contrary to guidelines?
  • ?Would provider education improve guideline adherence?

Trust & Context

Key Stat:
Evidence Grade:
Large population-based dataset with validated methodology, but self-reported outcomes and limited state coverage place evidence at moderate.
Study Age:
PRAMS data from 2017-2020.
Original Title:
Prenatal cannabis screening and counseling practices by state recreational legalization status: A multi-state examination of PRAMS data (2017-2020).
Published In:
Drug and alcohol dependence reports, 17, 100385 (2025)
Database ID:
RTHC-07674

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

Are pregnant women being told it's okay to use cannabis?

A small but concerning percentage (about 2-3%) were advised to use cannabis at prenatal visits, and this was higher in legalization states. This conflicts with current ACOG guidelines recommending against prenatal cannabis use.

Does legalization improve prenatal cannabis screening?

Yes. Women in states with recreational legalization were significantly more likely to be asked about cannabis use and advised against it during pregnancy, though overall guideline adherence was still low.

Read More on RethinkTHC

Cite This Study

RTHC-07674·https://rethinkthc.com/research/RTHC-07674

APA

Skelton, Kara R; Iobst, Stacey E; Benjamin-Neelon, Sara E. (2025). Prenatal cannabis screening and counseling practices by state recreational legalization status: A multi-state examination of PRAMS data (2017-2020).. Drug and alcohol dependence reports, 17, 100385. https://doi.org/10.1016/j.dadr.2025.100385

MLA

Skelton, Kara R, et al. "Prenatal cannabis screening and counseling practices by state recreational legalization status: A multi-state examination of PRAMS data (2017-2020).." Drug and alcohol dependence reports, 2025. https://doi.org/10.1016/j.dadr.2025.100385

RethinkTHC

RethinkTHC Research Database. "Prenatal cannabis screening and counseling practices by stat..." RTHC-07674. Retrieved from https://rethinkthc.com/research/skelton-2025-prenatal-cannabis-screening-and

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.