Sexual Abuse in Childhood Predicted Cannabis Use in Lithuanian Young Adults, but Verbal Abuse Did Not

Among 709 Lithuanian young adults, childhood sexual abuse predicted higher cannabis, alcohol, nicotine, and heavy drug use, while verbal abuse showed unexpected negative associations with substance use.

Sinkevicius, Liudas Vincentas et al.·International journal of environmental research and public health·2025·Moderate EvidenceObservational
RTHC-07671ObservationalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Moderate Evidence
Sample
N=709

What This Study Found

Sexual abuse predicted higher levels of cannabis, alcohol, nicotine, and heavy psychoactive substance use. Physical maltreatment predicted higher alcohol use. Witnessing interpersonal violence predicted only nicotine use. Unexpectedly, verbal abuse showed significant negative associations across several substance categories. Family addiction history was not significantly associated with substance use.

Key Numbers

709 participants aged 18-29. Sexual abuse predicted cannabis (CUDIT-R), alcohol (AUDIT), nicotine, and heavy substance use (ASSIST). Physical maltreatment predicted alcohol use. Verbal abuse negatively associated with several substance categories. Family addiction history not significant.

How They Did This

Cross-sectional study of 709 Lithuanian young adults aged 18-29 who completed an online survey. ACEs measured using adapted items and the MACE questionnaire. Substance use assessed via CUDIT-R, AUDIT, ASSIST, and self-report. Structural equation modeling tested predictive relationships.

Why This Research Matters

This is among the first studies in Lithuania to differentiate between types of adverse childhood experiences and their specific substance use outcomes, challenging the common practice of simply summing ACE scores.

The Bigger Picture

The finding that not all ACEs equally predict substance use, and that verbal abuse may even show a protective association, challenges simplistic models of childhood adversity and addiction. It suggests that the type of adverse experience matters more than the total count.

What This Study Doesn't Tell Us

Cross-sectional design prevents causal conclusions. Self-reported ACEs subject to recall bias. Online convenience sample may not be representative. Lithuanian-specific cultural context may limit generalizability. Verbal abuse finding is unexpected and needs replication.

Questions This Raises

  • ?Why does verbal abuse show negative associations with substance use?
  • ?Would longitudinal data confirm the specific ACE-substance use pathways?

Trust & Context

Key Stat:
Evidence Grade:
Adequate sample size with validated instruments and sophisticated modeling, but cross-sectional design and convenience sample limit to moderate.
Study Age:
Recent cross-sectional study from Lithuania.
Original Title:
Exploring Pathways from Childhood Adversity to Substance Use in Young Adults.
Published In:
International journal of environmental research and public health, 22(11) (2025)
Database ID:
RTHC-07671

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

Do all types of childhood trauma increase substance use risk?

No. This study found sexual abuse and physical maltreatment predicted substance use, but verbal abuse showed the opposite pattern, and family addiction history had no significant effect.

Does childhood sexual abuse predict cannabis use specifically?

Yes. Sexual abuse was the only ACE type that predicted cannabis use, along with alcohol, nicotine, and heavy psychoactive substance use in this Lithuanian sample.

Read More on RethinkTHC

Cite This Study

RTHC-07671·https://rethinkthc.com/research/RTHC-07671

APA

Sinkevicius, Liudas Vincentas; Sakalauskaite, Sandra; Poskus, Mykolas Simas; Pilkauskaite Valickiene, Rasa; Serapinas, Danielius. (2025). Exploring Pathways from Childhood Adversity to Substance Use in Young Adults.. International journal of environmental research and public health, 22(11). https://doi.org/10.3390/ijerph22111608

MLA

Sinkevicius, Liudas Vincentas, et al. "Exploring Pathways from Childhood Adversity to Substance Use in Young Adults.." International journal of environmental research and public health, 2025. https://doi.org/10.3390/ijerph22111608

RethinkTHC

RethinkTHC Research Database. "Exploring Pathways from Childhood Adversity to Substance Use..." RTHC-07671. Retrieved from https://rethinkthc.com/research/sinkevicius-2025-exploring-pathways-from-childhood

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.