Cannabis use after Canadian legalization increased mainly among people without mental health problems

Across nearly 93,000 Canadians surveyed over five years, cannabis use increased mainly among those without mental health conditions, while people with anxiety, depression, bipolar disorder, PTSD, or schizophrenia showed few changes in use after legalization.

Rundle, Samantha et al.·Lancet regional health. Americas·2026·Strong EvidenceCross-Sectional
RTHC-08593Cross SectionalStrong Evidence2026RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Strong Evidence
Sample
Not reported

What This Study Found

Past 12-month cannabis use increased from pre-legalization among those with anxiety (AOR 1.33) in the year immediately following legalization. Daily and 12-month use increased among Canadians not reporting mental health problems. No other pre-post legalization differences were observed among individuals with bipolar disorder, PTSD, or schizophrenia.

Key Numbers

92,843 Canadians across 6 annual surveys (2018-2023). Cannabis use increase among those with anxiety: AOR 1.33 (95% CI 1.15-1.53) in 2019 only. Increases in daily and 12-month use observed among those without mental health problems. No significant changes for bipolar, PTSD, or schizophrenia.

How They Did This

Data from the International Cannabis Policy Study's annual repeat cross-sectional surveys in Canada from 2018 to 2023 (one year pre- to five years post-legalization). Analysis included 92,843 Canadians aged 16-65. Adjusted logistic regression examined changes in daily and past 12-month use by mental health status.

Why This Research Matters

A major concern about legalization is that vulnerable populations, particularly those with mental health conditions, would increase cannabis use. This large-scale Canadian study provides reassuring evidence that the increase in use was driven primarily by people without mental health problems.

The Bigger Picture

This finding from the Lancet Regional Health suggests that legalization did not disproportionately increase cannabis use among the most vulnerable Canadians. The temporary increase among people with anxiety in the first year after legalization may reflect a specific subgroup exploring cannabis for symptom management, though this effect did not persist.

What This Study Doesn't Tell Us

Repeat cross-sectional design means different people were surveyed each year. Self-reported mental health conditions may not match clinical diagnoses. Cannabis use is also self-reported. The study cannot capture changes within individuals over time. Legalization effects may take longer than five years to fully manifest.

Questions This Raises

  • ?Why did the anxiety-related increase in use not persist beyond the first year?
  • ?Are people with mental health conditions self-regulating their cannabis use?
  • ?Would clinical populations (rather than self-reported) show different patterns?

Trust & Context

Key Stat:
Cannabis use post-legalization increased among Canadians without mental health problems, not among those with conditions
Evidence Grade:
Large-scale (n=92,843) national repeat cross-sectional study published in Lancet Regional Health, though limited by cross-sectional design.
Study Age:
Published in 2026, covering 2018-2023.
Original Title:
The prevalence of cannabis use pre-versus post-cannabis legalization in Canada by mental health status: findings from national repeat cross-sectional surveys.
Published In:
Lancet regional health. Americas, 55, 101373 (2026)
Database ID:
RTHC-08593

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Did legalization increase cannabis use among people with mental health conditions?

Mostly no. The only significant increase was among people with anxiety in the first year after legalization, which did not persist. People with depression, bipolar disorder, PTSD, and schizophrenia showed no significant changes.

Who did increase their cannabis use after legalization?

Canadians who did not report mental health problems showed increases in both daily and past 12-month cannabis use over the five years following legalization.

Read More on RethinkTHC

Cite This Study

RTHC-08593·https://rethinkthc.com/research/RTHC-08593

APA

Rundle, Samantha; Iraniparast, Maryam; Hammond, David. (2026). The prevalence of cannabis use pre-versus post-cannabis legalization in Canada by mental health status: findings from national repeat cross-sectional surveys.. Lancet regional health. Americas, 55, 101373. https://doi.org/10.1016/j.lana.2026.101373

MLA

Rundle, Samantha, et al. "The prevalence of cannabis use pre-versus post-cannabis legalization in Canada by mental health status: findings from national repeat cross-sectional surveys.." Lancet regional health. Americas, 2026. https://doi.org/10.1016/j.lana.2026.101373

RethinkTHC

RethinkTHC Research Database. "The prevalence of cannabis use pre-versus post-cannabis lega..." RTHC-08593. Retrieved from https://rethinkthc.com/research/rundle-2026-the-prevalence-of-cannabis

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.