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Study breakdown

Most Tobacco-Cannabis Co-Users Started With Nicotine E-Cigarettes Before Cannabis

Cross SectionalModerate evidence
The takeaway

Among 6,131 co-users, about 71% tried tobacco first, with nicotine e-cigarettes the most common gateway product, especially among younger users.

Substance use prevention professionals, school health educators, and policymakers.

71% of co-users tried tobacco first; ~60% started with nicotine e-cigarettes

What the researchers found

38.4% of participants co-used tobacco and cannabis. Among co-users, 70.9% tried tobacco first, with e-cigarettes being the first tobacco product for ~60% of those who started with tobacco.

Why it matters

Understanding the sequence from e-cigarettes to cannabis can help design prevention programs targeting the most common entry point.

The numbers in context

6,131 participants. 38.4% co-used. 70.9% tried tobacco first. ~60% started with e-cigarettes.

How the study worked

Cross-sectional national survey of 6,131 participants aged 13-40 reporting use of 17 tobacco and cannabis products.

What this study cannot tell us

Cross-sectional with retrospective recall. Does not establish causation.

How to read the evidence

Large national survey with detailed product data, but cross-sectional design limits causal inference.

When this study was published

Published in 2024.

The bigger picture

For today's generation, nicotine e-cigarettes may serve as initial substance exposure preceding cannabis, a different sequence from previous generations.

Questions still open

  • Would reducing e-cigarette access decrease cannabis initiation?
  • Is the sequence causal or reflecting shared risk factors?

Common questions

Do people start with tobacco or cannabis first?
About 71% of co-users tried tobacco first, with e-cigarettes the most common first product among younger users.
Are e-cigarettes a gateway to cannabis?
Most co-users vaped nicotine before cannabis, but this does not prove causation.

Read the original research

Products and patterns through which adolescents, young adults, and adults initiate co-use of tobacco and cannabis.

Addictive behaviors, 158, 108105

Citation

McCauley, Devin M; Liu, Jessica; Gaiha, Shivani Mathur; Halpern-Felsher, Bonnie. (2024). Products and patterns through which adolescents, young adults, and adults initiate co-use of tobacco and cannabis.. Addictive behaviors, 158, 108105. https://doi.org/10.1016/j.addbeh.2024.108105

Explore the wider topic