Heart transplant programs disagree on how to handle cannabis use, with state legality shaping policies

A survey of 140 transplant clinicians found significant disagreement on cannabis policies for heart transplant candidates, with programs in legal states more accepting of cannabis use and more likely to have formal policies.

Ilonze, Onyedika J et al.·PloS one·2024·Preliminary EvidenceObservational
RTHC-05397ObservationalPreliminary Evidence2024RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Preliminary Evidence
Sample
Not reported

What This Study Found

Whether cannabis was legal in the respondent's state significantly shaped clinical practices. Programs where cannabis was legal were more tolerant of higher use frequencies before listing exclusion (p = 0.033), more supportive of validated screening questionnaires (p = 0.011), and more likely to have formal policies addressing medical cannabis (p = 0.0001). Most clinicians agreed six months of abstinence was sufficient before listing.

Key Numbers

140 clinicians; 41.4% cardiologists; significant differences by state legality for: acceptable use frequency (p = 0.033), screening questionnaire utility (p = 0.011), program allows prescribed cannabis (p < 0.0001), formal policy exists (p = 0.0001); most agreed on 6 months abstinence

How They Did This

Web-based survey of 140 clinicians involved in heart transplant care (cardiologists 41.4%, surgeons 7.1%, pharmacists 9.3%, plus advanced practice providers and coordinators). Responses compared between those in states where cannabis was legal versus illegal.

Why This Research Matters

The lack of consensus on cannabis policies for heart transplant candidates means patients may be denied or accepted for transplant based largely on geography rather than evidence.

The Bigger Picture

As cannabis legalization expands, the transplant community needs evidence-based consensus guidelines to prevent geographic lottery in transplant access for cannabis-using patients.

What This Study Doesn't Tell Us

Survey response rate not reported; self-selected respondents may not represent all programs; responses reflect stated practices which may differ from actual behavior; cannot assess patient outcomes associated with different policies

Questions This Raises

  • ?Does cannabis use actually affect heart transplant outcomes?
  • ?Would standardized national guidelines reduce transplant access inequity for cannabis users?

Trust & Context

Key Stat:
140 transplant clinicians surveyed across legal/illegal states
Evidence Grade:
Clinician survey providing practice pattern data, but without response rates or patient outcome data to guide evidence-based policy.
Study Age:
2024 study
Original Title:
Cannabis use and heart transplant listing: A survey of clinician practices.
Published In:
PloS one, 19(12), e0310778 (2024)
Database ID:
RTHC-05397

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

How do transplant programs handle cannabis use differently?

Programs in states where cannabis is legal tolerate higher frequencies of use, are more likely to have formal policies addressing medical cannabis, and are more open to using validated screening tools. Programs where cannabis is illegal are more likely to prohibit pre- and post-transplant cannabis use entirely.

Is there any agreement among transplant programs?

Most clinicians agreed that six months of abstinence from cannabis should be sufficient before being listed for heart transplant. There was also general agreement that a validated cannabis use disorder screening questionnaire would be useful for evaluating transplant eligibility.

Read More on RethinkTHC

Cite This Study

RTHC-05397·https://rethinkthc.com/research/RTHC-05397

APA

Ilonze, Onyedika J; Knapp, Shannon M; Chernyak, Yelena; Page, Robert L; Boyd, LaKeisha J; Mazimba, Sula; Raman, Subha V; Enyi, Chioma O; Allen, Larry A; Breathett, Khadijah. (2024). Cannabis use and heart transplant listing: A survey of clinician practices.. PloS one, 19(12), e0310778. https://doi.org/10.1371/journal.pone.0310778

MLA

Ilonze, Onyedika J, et al. "Cannabis use and heart transplant listing: A survey of clinician practices.." PloS one, 2024. https://doi.org/10.1371/journal.pone.0310778

RethinkTHC

RethinkTHC Research Database. "Cannabis use and heart transplant listing: A survey of clini..." RTHC-05397. Retrieved from https://rethinkthc.com/research/ilonze-2024-cannabis-use-and-heart

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.