One in Five Cannabis-Related ER Visits Among Young People Involved Fainting

Analyzing NEISS data from 2019-2022, researchers found that among 24,922 cannabis-associated injuries in young people aged 15-24, 5,400 (21.7%) also involved syncope. The prevalence of syncope among cannabis users was 8.6 times higher than among non-users (PR=8.6, 95% CI: 7.1-10.2). Most injuries were to the head and neck, with falls being the most common mechanism, suggesting syncope leads to fall-related injuries.

Cross-sectional study using the National Electronic Injury Surveillance System (2019-2022). Identified cannabis-associated injuries among 15-24 year olds presenting to emergency departments and screened for concurrent syncope. Calculated prevalence ratios comparing syncopal rates between cannabis users and non-users.

Cannabis-related syncope is underrecognized as a cause of injury in young people. The 8.6-fold higher prevalence suggests a strong association that may be clinically significant, particularly as cannabis potency and use increase.

Syncope after cannabis use is likely related to orthostatic hypotension (blood pressure drop on standing), a known cardiovascular effect of THC. As cannabis products become more potent, the incidence and severity of syncope-related injuries may increase.

NEISS captures injuries leading to ER visits, not all cannabis-related syncope events. Cannot determine causation. Cannabis association based on screening, not confirmed as the cause of syncope. Cannot assess THC dose, product type, or timing relative to use. No information on underlying cardiovascular conditions.