Recreational cannabis laws had limited overall effect on drinking and smoking, but varied by group
A study of 4.8 million US adults found that recreational cannabis laws had limited overall effects on alcohol and tobacco use, but when dispensaries were operational, small decreases in current drinking and smoking emerged, with effects varying by age, sex, race, and income.
Quick Facts
What This Study Found
Using law passage as the measure, recreational cannabis laws showed no association with alcohol or tobacco use. But using operational dispensary opening, these laws were associated with a 0.95 percentage point decrease in current drinking and 0.48 percentage point decrease in current smoking. Subgroup analysis revealed heterogeneous effects across demographics.
Key Numbers
Sample: 4.8 million adults, 2012-2022. With operational dispensaries: current drinking decreased 0.95 percentage points (95% CI 0.09-1.80), current smoking decreased 0.48 percentage points (95% CI 0.10-0.85). Some subgroups showed increased smokeless tobacco use.
How They Did This
Researchers analyzed cross-sectional data from 4.8 million adults in the 2012-2022 Behavioral Risk Factor Surveillance System using a difference-in-differences approach, adjusting for individual characteristics and state-level factors. Two definitions of cannabis law implementation were tested: law passage and operational dispensary opening.
Why This Research Matters
Whether cannabis legalization increases or decreases use of other substances has major public health implications. This study suggests the answer depends on how you measure legalization and which population groups you examine, adding important nuance to a polarized debate.
The Bigger Picture
The distinction between law passage and dispensary operations is key. Laws on the books may have little effect until people can actually purchase cannabis legally. The heterogeneous effects across demographics suggest that cannabis substitution for alcohol and tobacco is not universal but depends on factors like age, sex, race, and socioeconomic status.
What This Study Doesn't Tell Us
Cross-sectional survey data with self-reported substance use. The difference-in-differences approach relies on parallel trends assumptions that may not hold for all states. The small effect sizes, while statistically significant, may have limited clinical or public health significance. Cannot distinguish between substitution and complementary use.
Questions This Raises
- ?Why do effects differ by demographic groups?
- ?Is the decrease in drinking and smoking driven by substitution with cannabis, or by other policy changes that correlate with legalization?
- ?What explains the increase in smokeless tobacco use in some groups?
Trust & Context
- Key Stat:
- Operational dispensaries associated with 0.95 percentage point drop in current drinking
- Evidence Grade:
- Large population study with 4.8 million adults using a rigorous difference-in-differences design, but limited by self-reported cross-sectional data.
- Study Age:
- Published in 2025, using data from 2012 to 2022.
- Original Title:
- The Effects of Recreational Cannabis Laws on Alcohol and Tobacco Use Among U.S. Adults, 2012-2022.
- Published In:
- American journal of preventive medicine, 68(5), 1032-1040 (2025)
- Authors:
- De, Prabal K(2), Sun, Ruoyan(4)
- Database ID:
- RTHC-06324
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
Does cannabis legalization reduce alcohol use?
In this study, a small decrease in current drinking appeared only after dispensaries opened, not when laws were passed. The effect was modest (less than 1 percentage point) and varied across demographic groups.
Did legalization affect tobacco use?
Current cigarette smoking decreased slightly with operational dispensaries, but some groups showed increased smokeless tobacco use, suggesting complex and varied substitution patterns.
Why does it matter whether dispensaries are open?
Passing a law does not immediately change behavior. Only when cannabis becomes physically available through legal dispensaries do consumers have a practical alternative to alcohol or tobacco.
Read More on RethinkTHC
Cite This Study
https://rethinkthc.com/research/RTHC-06324APA
De, Prabal K; Sun, Ruoyan. (2025). The Effects of Recreational Cannabis Laws on Alcohol and Tobacco Use Among U.S. Adults, 2012-2022.. American journal of preventive medicine, 68(5), 1032-1040. https://doi.org/10.1016/j.amepre.2025.01.024
MLA
De, Prabal K, et al. "The Effects of Recreational Cannabis Laws on Alcohol and Tobacco Use Among U.S. Adults, 2012-2022.." American journal of preventive medicine, 2025. https://doi.org/10.1016/j.amepre.2025.01.024
RethinkTHC
RethinkTHC Research Database. "The Effects of Recreational Cannabis Laws on Alcohol and Tob..." RTHC-06324. Retrieved from https://rethinkthc.com/research/de-2025-the-effects-of-recreational
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.