Psychological distress nearly tripled cannabis use frequency among pregnant women in the US

Analysis of 3,373 pregnant women found those experiencing serious psychological distress used cannabis nearly three times as many days per month compared to those without distress.

David, Ayomide T et al.·Preventive medicine·2023·Moderate EvidenceCross-Sectional
RTHC-04486Cross SectionalModerate Evidence2023RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Among 3,373 pregnant women aged 18-44, approximately 6% experienced serious psychological distress in the past 30 days. Compared to those without SPD, pregnant women with SPD showed significantly higher rates of cigarette smoking (IRR=2.1), binge drinking days (IRR=5.1), and cannabis use days (IRR=2.9). All associations remained significant after adjusting for covariates.

Key Numbers

3,373 pregnant women; 6% experienced SPD; cannabis use days IRR=2.9 (95% CI 1.3-6.5); cigarettes IRR=2.1 (95% CI 1.1-4.5); binge drinking days IRR=5.1 (95% CI 1.7-15.4)

How They Did This

Descriptive and negative binomial regression analyses of the 2015-2019 National Survey on Drug Use and Health (NSDUH). Examined associations between serious psychological distress and quantity/frequency of tobacco, alcohol, and cannabis use among 3,373 pregnant women aged 18-44.

Why This Research Matters

The strong link between psychological distress and prenatal substance use suggests that treating maternal mental health could reduce substance exposure during pregnancy more effectively than substance-specific interventions alone.

The Bigger Picture

When pregnant women use substances at higher rates during psychological distress, interventions that only target substance use without addressing the underlying mental health need may miss the primary driver.

What This Study Doesn't Tell Us

Cross-sectional NSDUH data cannot establish causation. Self-reported substance use likely underestimates true use during pregnancy. SPD is a screening measure, not a clinical diagnosis. Cannot distinguish between types of psychological distress.

Questions This Raises

  • ?Would treating maternal depression and anxiety reduce prenatal cannabis use as a secondary effect?
  • ?Are women using cannabis specifically to self-medicate psychological distress during pregnancy?

Trust & Context

Key Stat:
Serious psychological distress associated with 2.9x more cannabis use days during pregnancy
Evidence Grade:
Large nationally representative survey with adjusted regression models, though cross-sectional design and self-reported data have inherent limitations.
Study Age:
Published 2023 using 2015-2019 data
Original Title:
Exploring the associations between serious psychological distress and the quantity or frequency of tobacco, alcohol, and cannabis use among pregnant women in the United States.
Published In:
Preventive medicine, 177, 107770 (2023)
Database ID:
RTHC-04486

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Does mental health affect cannabis use during pregnancy?

Yes. Pregnant women experiencing serious psychological distress used cannabis on nearly three times as many days per month as those without distress, suggesting mental health treatment could reduce prenatal substance exposure.

How common is psychological distress among pregnant women?

About 6% of pregnant women in this national sample experienced serious psychological distress, and those women showed significantly elevated rates of cannabis, tobacco, and alcohol use.

Read More on RethinkTHC

Cite This Study

RTHC-04486·https://rethinkthc.com/research/RTHC-04486

APA

David, Ayomide T; Sharma, Vinita; Bittencourt, Lorna; Gurka, Kelly K; Perez-Carreño, Juan Guillermo; Lopez-Quintero, Catalina. (2023). Exploring the associations between serious psychological distress and the quantity or frequency of tobacco, alcohol, and cannabis use among pregnant women in the United States.. Preventive medicine, 177, 107770. https://doi.org/10.1016/j.ypmed.2023.107770

MLA

David, Ayomide T, et al. "Exploring the associations between serious psychological distress and the quantity or frequency of tobacco, alcohol, and cannabis use among pregnant women in the United States.." Preventive medicine, 2023. https://doi.org/10.1016/j.ypmed.2023.107770

RethinkTHC

RethinkTHC Research Database. "Exploring the associations between serious psychological dis..." RTHC-04486. Retrieved from https://rethinkthc.com/research/david-2023-exploring-the-associations-between

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.