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Study breakdown

Adolescent vaping of THC, CBD, and synthetic cannabinoids all increased from 2021 to 2023

Cross SectionalStrong evidence
The takeaway

Among nearly 70,000 US middle and high schoolers, vaping of all cannabinoid types increased from 2021 to 2023, with 2.55 million teens vaping THC and synthetic cannabinoid use doubling among 11-13 year olds.

School health officials, pediatricians, youth substance prevention programs

2.55 million US adolescents were vaping THC in 2023, with synthetic cannabinoid use doubling among 11-13 year olds

What the researchers found

Significant increases in vaping of THC, CBD, and synthetic cannabinoids from 2021-2023; THC vaping peaked in 2022 while synthetic continued rising; prevalence higher among females than males in 2023; use doubled among 11-13 year olds.

Why it matters

The rise in synthetic cannabinoid vaping among the youngest adolescents is alarming given unknown health effects, while overall cannabis vaping continues spreading across all cannabinoid types.

The numbers in context

69,899 students; 2023: 7.4% (2.55M) vaping THC, 2.9% (999K) vaping CBD, 1.8% (620K) vaping synthetic cannabinoids; females exceeded males in 2023; 11-13 year old THC and synthetic use doubled 2021-2023.

How the study worked

Three waves of National Youth Tobacco Survey (2021-2023); 69,899 US middle and high school students aged 11-18; weighted prevalence estimates by year, age, and sex.

What this study cannot tell us

Self-reported data; students may not know what cannabinoid they are vaping; "don't know" responses for synthetics tripled (awareness issue); school-based survey misses dropouts.

How to read the evidence

Large nationally representative youth survey with three annual waves, though self-reported data and potential misidentification of substances are limitations.

When this study was published

Published 2025, data from 2021-2023

The bigger picture

The rapid growth of synthetic cannabinoid vaping among adolescents represents an emerging public health crisis with unknown long-term consequences.

Questions still open

  • Why are females now vaping cannabinoids more than males? What are the health effects of synthetic cannabinoid vaping in adolescents? Are students aware they may be consuming synthetic cannabinoids?

Common questions

How many teens are vaping cannabis?
An estimated 2.55 million US adolescents (7.4%) were vaping THC in 2023, with nearly 1 million vaping CBD and 620,000 vaping synthetic cannabinoids.
Which age group saw the biggest increase?
The youngest group (ages 11-13) saw THC and synthetic cannabinoid vaping prevalence double between 2021 and 2023.

Read the original research

Adolescent Cannabis Vaping Trends (2021-2023): Delta-9-Tetrahydrocannabinol, Cannabidiol, and Synthetic Cannabinoids.

American journal of preventive medicine, 69(6), 107655

Citation

Chung, Jack; Lim, Carmen C W; Stjepanović, Daniel; Hall, Wayne; Connor, Jason P; Chan, Gary C K. (2025). Adolescent Cannabis Vaping Trends (2021-2023): Delta-9-Tetrahydrocannabinol, Cannabidiol, and Synthetic Cannabinoids.. American journal of preventive medicine, 69(6), 107655. https://doi.org/10.1016/j.amepre.2025.107655

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