Cannabis improved mood and reduced anxiety but did not change emotion regulation performance in young adults

In a remote within-subjects study, young adults reported better mood and less anxiety while high but showed no changes in implicit or explicit emotion regulation tasks.

Cavalli, Jessica M et al.·Human psychopharmacology·2025·Preliminary EvidencePilot Study
RTHC-06174Pilot StudyPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Pilot Study
Evidence
Preliminary Evidence
Sample
N=12

What This Study Found

Participants reported more positive mood and decreased anxiety while intoxicated, but no evidence that acute high-potency cannabis affected implicit (Emotional Go/No-Go) or explicit (cognitive reappraisal) emotion regulation performance.

Key Numbers

12 participants; ages 21-30; all used cannabis at least 1 day/week; tested sober and intoxicated in counterbalanced order.

How They Did This

Remote within-subjects design; 12 young adults (ages 21-30, using cannabis 1+ day/week) completed emotion regulation measures while sober and acutely intoxicated in counterbalanced order; participants smoked cannabis flower at home via videoconferencing observation.

Why This Research Matters

Many people report using cannabis to manage emotions, but this study suggests the subjective mood improvement may not reflect actual changes in emotion regulation ability.

The Bigger Picture

The disconnect between subjective mood improvement and unchanged cognitive emotion regulation raises questions about whether cannabis truly helps people manage emotions or just makes them feel better temporarily.

What This Study Doesn't Tell Us

Very small sample (n=12); only frequent cannabis users included, who may have tolerance; limited to two emotion regulation tasks; no dose standardization; single-session design.

Questions This Raises

  • ?Would infrequent users show different results?
  • ?Does chronic cannabis use gradually impair emotion regulation even if acute effects are neutral?
  • ?Could larger samples detect subtle effects?

Trust & Context

Key Stat:
Zero measurable change in emotion regulation despite reported mood improvement
Evidence Grade:
Novel remote methodology but very small sample and limited to regular users, making it difficult to draw firm conclusions.
Study Age:
Published 2025
Original Title:
A Naturalistic Examination of the Acute Effects of High-Potency Cannabis on Emotion Regulation Among Young Adults: A Pilot Study.
Published In:
Human psychopharmacology, 40(1), e2915 (2025)
Database ID:
RTHC-06174

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A small preliminary study to test whether a larger study is feasible.

What do these levels mean? →

Frequently Asked Questions

Did cannabis help with emotion regulation?

Participants felt better (more positive mood, less anxiety) but performed no differently on tasks measuring actual emotion regulation ability.

What was the study design?

A remote within-subjects design where 12 regular cannabis users completed tasks sober and intoxicated, observed via video call while smoking at home.

Read More on RethinkTHC

Cite This Study

RTHC-06174·https://rethinkthc.com/research/RTHC-06174

APA

Cavalli, Jessica M; Cuttler, Carrie; Cservenka, Anita. (2025). A Naturalistic Examination of the Acute Effects of High-Potency Cannabis on Emotion Regulation Among Young Adults: A Pilot Study.. Human psychopharmacology, 40(1), e2915. https://doi.org/10.1002/hup.2915

MLA

Cavalli, Jessica M, et al. "A Naturalistic Examination of the Acute Effects of High-Potency Cannabis on Emotion Regulation Among Young Adults: A Pilot Study.." Human psychopharmacology, 2025. https://doi.org/10.1002/hup.2915

RethinkTHC

RethinkTHC Research Database. "A Naturalistic Examination of the Acute Effects of High-Pote..." RTHC-06174. Retrieved from https://rethinkthc.com/research/cavalli-2025-a-naturalistic-examination-of

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.