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Study breakdown

Study of 926 boys identifies six developmental patterns of substance use, with impulsive sensation-seekers at highest risk

Longitudinal CohortModerate evidence
The takeaway

Among 926 boys from low-income neighborhoods followed through adolescence, six distinct patterns of co-occurring alcohol, marijuana, and other drug use emerged, with impulsive sensation-seekers showing the earliest onset and most severe polysubstance use.

Prevention researchers, school counselors, child psychologists, and parents of at-risk youth.

61% were non/low users; impulsive sensation-seekers had earliest, most severe use

What the researchers found

Latent growth mixture modeling revealed six developmental patterns: 61% were non/low users, while five polysubstance groups varied in severity. Higher sensation-seeking and lower anxiety were common across all user groups. Low self-esteem and family risk factors differentiated all users from later-onset users. Higher impulsivity and school problems characterized the most severe early-onset groups.

Why it matters

Identifying preadolescent risk profiles before substance use begins could enable targeted prevention programs for the highest-risk youth.

The numbers in context

926 boys; 61% were non/low users; 5 polysubstance groups varied in severity. Impulsive sensation-seekers with low anxiety and low self-esteem accumulated the most risk factors.

How the study worked

Longitudinal study of 926 boys from low-socioeconomic urban neighborhoods. Latent growth mixture modeling identified co-occurring substance use patterns through adolescence. Preadolescent risk factors (personality, family, school) were tested as predictors.

What this study cannot tell us

Only boys studied (no girls). Low-socioeconomic urban sample limits generalizability. Self-reported substance use. Preadolescent measures may not capture all relevant risk factors. Historical cohort may not reflect current substance availability.

How to read the evidence

Longitudinal design with validated modeling approach, but limited to boys from low-income neighborhoods.

When this study was published

Published in 2022.

The bigger picture

The finding that personality traits measurable before adolescence predict substance use trajectories supports a shift from universal prevention programs toward indicated prevention targeting high-risk youth.

Questions still open

  • Do the same patterns apply to girls? Would early intervention targeting impulsive sensation-seekers actually prevent polysubstance use? How do these trajectories interact with cannabis legalization?

Common questions

Can you predict which kids will use multiple substances?
This study found that preadolescent traits, specifically high sensation-seeking, high impulsivity, low anxiety, low self-esteem, family problems, and school difficulties, together predicted the most severe patterns of combined alcohol, marijuana, and other drug use during adolescence.
How common was polysubstance use?
About 39% of boys fell into one of five polysubstance use groups of varying severity. The remaining 61% were non-users or very low users throughout adolescence.

Read the original research

Alcohol, Marijuana and Other Illicit Drugs Use Throughout Adolescence: Co-occurring Courses and Preadolescent Risk-Factors.

Child psychiatry and human development, 53(6), 1194-1206

Citation

Carbonneau, Rene; Vitaro, Frank; Brendgen, Mara; Tremblay, Richard E. (2022). Alcohol, Marijuana and Other Illicit Drugs Use Throughout Adolescence: Co-occurring Courses and Preadolescent Risk-Factors.. Child psychiatry and human development, 53(6), 1194-1206. https://doi.org/10.1007/s10578-021-01202-w

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