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Study breakdown

Poison Center Calls for Edible Marijuana Exposures Rose Steadily, With Children Under 5 Most Affected

Cross SectionalModerate evidence
The takeaway

Analysis of 430 US poison center calls for edible marijuana found 91% came from states with decriminalized cannabis, calls increased every year, and children under 5 were the most common age group affected.

Parents, caregivers, and policymakers interested in the risks of edible cannabis products.

Children under 5 were the most common age group in edible marijuana poison center calls

What the researchers found

Researchers analyzed edible marijuana exposure calls reported to US poison centers from 2013 through 2015.

Of 430 calls, 91% occurred in states with decriminalized medical or recreational marijuana. Colorado (166 calls) and Washington (96 calls) had the most. The number of calls increased every year of the study.

Children under 5 were the most common age group affected (109 calls, 25%), followed by teens aged 13-19 (78 calls). The most frequent effects were drowsiness (43%), rapid heart rate (31%), agitation (14%), and confusion (14%). Young children were more likely to experience drowsiness, uncoordinated movement, and red eyes.

Three patients (ages 4, 10, and 57) required intubation for respiratory support. No deaths were reported. Most cases were either managed at home (23%) or treated and released from the emergency department (50%).

Why it matters

Edible marijuana products can be indistinguishable from regular food items, making accidental ingestion by children a significant risk. The delayed onset of edible effects (compared to smoking) can also lead adults to consume additional doses, resulting in overdose.

The numbers in context

430 calls total. Colorado: 166, Washington: 96. Children under 5: 109 calls (25%). Ages 13-19: 78 calls. 91% from decriminalized states. 3 patients intubated. 12 admitted to critical care (3%). No deaths.

How the study worked

Analysis of single-substance human exposure calls coded to marijuana edibles (brownies, candies, cookies, beverages, other foods) reported to the National Poison Data System from January 2013 to December 2015.

What this study cannot tell us

Poison center data capture only cases that are called in and may undercount actual exposures. The increasing calls could partly reflect greater awareness of poison center reporting codes for edibles rather than purely increasing exposures. The study could not determine the exact THC dose consumed in most cases.

How to read the evidence

This is a national poison center data analysis providing moderate-quality surveillance data on a specific exposure pattern.

When this study was published

Published in 2016, covering 2013-2015. Edible marijuana regulations (packaging, dosing) have evolved substantially since then.

The bigger picture

This study captured the early years of legal edible marijuana availability. Since then, many states have implemented child-resistant packaging and serving size regulations, though accidental pediatric exposures remain a concern as legalization continues to expand.

Questions still open

  • Have child-resistant packaging regulations reduced accidental pediatric exposures? What is the most effective strategy for preventing edible marijuana ingestion by young children?

Common questions

Can edible marijuana seriously harm a child?
Most pediatric cases in this study involved drowsiness and mild effects, but 3 patients required intubation (breathing support). While no deaths were reported, edible marijuana ingestion in young children can cause significant sedation, respiratory depression, and occasionally require critical care.
Why are edible exposures increasing?
The study suggested multiple factors: delayed THC absorption leading to dose miscalculation, lagging packaging regulations in early legalization states, increased product availability, and growing awareness of poison center reporting codes for edible products.

Read the original research

Characterization of edible marijuana product exposures reported to United States poison centers.

Clinical toxicology (Philadelphia, Pa.), 54(9), 840-846

Citation

Cao, Dazhe; Srisuma, Sahaphume; Bronstein, Alvin C; Hoyte, Christopher O. (2016). Characterization of edible marijuana product exposures reported to United States poison centers.. Clinical toxicology (Philadelphia, Pa.), 54(9), 840-846.

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