The Sharpest Jump in Cannabis Use Occurred Between Adolescence and Young Adulthood for Low-Risk Perceivers

Among 58,034 Americans, the largest increase in cannabis use probability occurred between ages 12-17 and 18-25 specifically among people who perceived no or low risk from cannabis.

Burrow-Sánchez, Jason J et al.·American journal of health promotion : AJHP·2025·Strong EvidenceCross-Sectional
RTHC-06135Cross SectionalStrong Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Strong Evidence
Sample
N=58,034

What This Study Found

A significant interaction between age group and perceived risk predicted cannabis use. The sharpest increase in cannabis use probability occurred between adolescents (12-17) and young adults (18-25) among those with no or low risk perception. This suggests that adolescents who perceive cannabis as low-risk are primed for a major usage increase once they reach young adulthood.

Key Numbers

58,034 participants; significant age x perceived risk interaction; sharpest usage increase between 12-17 and 18-25 age groups for no/low risk perceivers; population-level nationally representative sample; 2021 data

How They Did This

Secondary analysis of the 2021 National Survey on Drug Use and Health (N=58,034, ages 12+). Binary logistic regression with complex sampling examined the interaction between age group and perceived risk on past 30-day cannabis use.

Why This Research Matters

Prevention programs that shape risk perception during adolescence could have outsized effects if they reach young people before the transition to adulthood, when low-risk perceiving adolescents appear most likely to start using cannabis.

The Bigger Picture

As cannabis legalization expands and perceived risk continues declining among young people, this finding suggests a growing pool of adolescents with low-risk perceptions who will sharply increase their use upon reaching adulthood. Prevention efforts targeting risk perception in early adolescence may be the most effective intervention window.

What This Study Doesn't Tell Us

Cross-sectional design cannot confirm that low risk perception causes later use, 2021 data from a single year, perceived risk and use measured simultaneously, cannot distinguish between accurate and inaccurate risk perceptions

Questions This Raises

  • ?Does changing risk perception in adolescence actually reduce adult cannabis use?
  • ?Is the risk perception-use relationship changing over time with legalization?
  • ?What specific aspects of risk perception (health, legal, social) matter most?

Trust & Context

Key Stat:
The sharpest cannabis use increase occurred between ages 12-17 and 18-25 among low-risk perceivers
Evidence Grade:
Very large nationally representative sample with appropriate complex survey analysis; cross-sectional limitation but strong population-level data
Study Age:
Published 2025
Original Title:
Past 30-Day Cannabis Use by Perception of Risk and Age Group: Implications for Prevention.
Published In:
American journal of health promotion : AJHP, 39(4), 619-626 (2025)
Database ID:
RTHC-06135

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

When does cannabis use increase the most?

The biggest jump in cannabis use occurs when people move from adolescence (12-17) to young adulthood (18-25), and this jump is largest among those who perceive cannabis as having no or low risk.

Does thinking cannabis is safe lead to using it?

This study found a strong interaction: people who perceived low risk from cannabis and were in the 18-25 age group had the highest probability of use, suggesting that risk perception established during adolescence may predict adult behavior.

Read More on RethinkTHC

Cite This Study

RTHC-06135·https://rethinkthc.com/research/RTHC-06135

APA

Burrow-Sánchez, Jason J; Cohen, Allison. (2025). Past 30-Day Cannabis Use by Perception of Risk and Age Group: Implications for Prevention.. American journal of health promotion : AJHP, 39(4), 619-626. https://doi.org/10.1177/08901171241312508

MLA

Burrow-Sánchez, Jason J, et al. "Past 30-Day Cannabis Use by Perception of Risk and Age Group: Implications for Prevention.." American journal of health promotion : AJHP, 2025. https://doi.org/10.1177/08901171241312508

RethinkTHC

RethinkTHC Research Database. "Past 30-Day Cannabis Use by Perception of Risk and Age Group..." RTHC-06135. Retrieved from https://rethinkthc.com/research/burrow-sanchez-2025-past-30day-cannabis-use

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.