Vomiting-related ER visits increased 29% in Colorado after cannabis legalization

Vomiting-related emergency department visits in Colorado rose from 119,312 in 2013 to 153,699 in 2018, with additional recreational dispensaries associated with increased visit rates.

Wang, George Sam et al.·JAMA network open·2021·Moderate EvidenceCross-Sectional
RTHC-03601Cross SectionalModerate Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Moderate Evidence
Sample
N=820,778

What This Study Found

Vomiting-related ED visits increased 29% over the study period. Each additional recreational dispensary was associated with a 3% increase in vomiting-related visits (IRR 1.03). However, counties with high baseline medical dispensary exposure experienced smaller increases than counties with no prior dispensaries (IRR 0.97).

Key Numbers

Total patients: 820,778. Visits 2013: 119,312. Visits 2018: 153,699. Increase: 29%. Recreational dispensary IRR: 1.03. Counties with prior medical dispensaries grew 5.8% slower. Female: 62%. Ages 0-18: 25%.

How They Did This

Cross-sectional analysis of 820,778 patients with vomiting-related ED claims reported to the Colorado Hospital Association from January 2013 to December 2018, examining the relationship between dispensary density and visit rates by county.

Why This Research Matters

This large-scale analysis provides population-level evidence connecting cannabis market expansion to increased vomiting-related healthcare utilization, likely reflecting cannabinoid hyperemesis syndrome.

The Bigger Picture

The finding that counties with established medical dispensaries saw slower increases suggests a possible habituation or education effect in markets with longer cannabis exposure.

What This Study Doesn't Tell Us

Cannot confirm cannabis as the cause of vomiting. ED claims data may include multiple visits by the same patient. No direct measure of cannabis use among patients presenting with vomiting.

Questions This Raises

  • ?Is the slower growth in counties with established dispensaries due to clinician awareness, consumer education, or demographic differences?
  • ?What proportion of these vomiting visits are actually CHS?

Trust & Context

Key Stat:
29% increase in vomiting-related ER visits over 5 years post-legalization
Evidence Grade:
Large population-level dataset with county-level dispensary data, but cannot directly link individual vomiting cases to cannabis use.
Study Age:
Published in 2021 using Colorado data from 2013-2018.
Original Title:
Changes in Emergency Department Encounters for Vomiting After Cannabis Legalization in Colorado.
Published In:
JAMA network open, 4(9), e2125063 (2021)
Database ID:
RTHC-03601

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Did cannabis legalization increase ER visits for vomiting?

Vomiting-related ER visits rose 29% in Colorado from 2013 to 2018, and each additional recreational dispensary was associated with a 3% increase in visit rates.

Did areas with existing medical marijuana dispensaries see the same increase?

No. Counties that already had medical dispensaries before recreational legalization experienced 5.8% slower growth in vomiting-related visits than counties with none.

Read More on RethinkTHC

Cite This Study

RTHC-03601·https://rethinkthc.com/research/RTHC-03601

APA

Wang, George Sam; Buttorff, Christine; Wilks, Asa; Schwam, Daniel; Tung, Gregory; Pacula, Rosalie Liccardo. (2021). Changes in Emergency Department Encounters for Vomiting After Cannabis Legalization in Colorado.. JAMA network open, 4(9), e2125063. https://doi.org/10.1001/jamanetworkopen.2021.25063

MLA

Wang, George Sam, et al. "Changes in Emergency Department Encounters for Vomiting After Cannabis Legalization in Colorado.." JAMA network open, 2021. https://doi.org/10.1001/jamanetworkopen.2021.25063

RethinkTHC

RethinkTHC Research Database. "Changes in Emergency Department Encounters for Vomiting Afte..." RTHC-03601. Retrieved from https://rethinkthc.com/research/wang-2021-changes-in-emergency-department

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.