Cannabis Smoking Linked to Wellens Syndrome, a Rare Warning of Impending Heart Attack
A young man with no CAD risk factors developed Wellens syndrome associated with cannabis smoking.
Quick Facts
What This Study Found
Young male, no risk factors, serial ECG changes of Wellens syndrome. Cannabis smoking history led to timely diagnosis. Required invasive treatment.
Key Numbers
Young male. No CAD risk factors. Minimally elevated troponin. Invasive strategy required.
How They Did This
Case report with serial ECGs and troponin monitoring.
Why This Research Matters
Wellens syndrome requires invasive treatment. Cannabis as a trigger in young patients without risk factors is clinically important.
The Bigger Picture
Clinicians should consider cannabis as a risk factor for ACS in young patients without traditional risk factors.
What This Study Doesn't Tell Us
Single case. Cannot prove causation.
Questions This Raises
- ?How often does cannabis trigger ACS?
- ?Should cannabis history change diagnostic approach for young chest pain?
Trust & Context
- Key Stat:
- Evidence Grade:
- Case report adding to cardiovascular risk literature.
- Study Age:
- 2025 case report.
- Original Title:
- Cannabis-Induced Wellens Syndrome: A Rising Cardiovascular Risk.
- Published In:
- Cureus, 17(7), e88068 (2025)
- Database ID:
- RTHC-07836
Evidence Hierarchy
Frequently Asked Questions
Can cannabis cause heart problems?
This case describes Wellens syndrome in a young man associated with cannabis, despite no traditional risk factors.
What is Wellens syndrome?
An ECG pattern warning of impending heart attack, requiring invasive treatment.
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Cite This Study
https://rethinkthc.com/research/RTHC-07836APA
Unal, Selin; Rattan, Keston; Khan, Mir Sulayman; Wang, Roy; Amro, Omar; Bukharovich, Inna. (2025). Cannabis-Induced Wellens Syndrome: A Rising Cardiovascular Risk.. Cureus, 17(7), e88068. https://doi.org/10.7759/cureus.88068
MLA
Unal, Selin, et al. "Cannabis-Induced Wellens Syndrome: A Rising Cardiovascular Risk.." Cureus, 2025. https://doi.org/10.7759/cureus.88068
RethinkTHC
RethinkTHC Research Database. "Cannabis-Induced Wellens Syndrome: A Rising Cardiovascular R..." RTHC-07836. Retrieved from https://rethinkthc.com/research/unal-2025-cannabisinduced-wellens-syndrome-a
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.