Older adults are the fastest-growing group of cannabis users, but research on how it affects aging brains and hearts is just beginning

A narrative review found that most older adults who use cannabis do so for medical purposes like pain and insomnia, but cardiovascular risks, cognitive effects during aging, and potential for treating neurodegeneration remain poorly studied.

Thayer, Rachel E et al.·Substance abuse and rehabilitation·2026·Moderate EvidenceNarrative Review
RTHC-08659Narrative ReviewModerate Evidence2026RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Narrative Review
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Most older adults who use cannabis report doing so for medical purposes, primarily targeting pain, insomnia, anxiety, and depression. Many do not discuss cannabis use with their medical providers. Emerging evidence from younger populations suggests cardiovascular risks of heavy use, but this has not been thoroughly studied in aging adults.

Key Numbers

Most older adult cannabis users report medical purposes. Common targets: pain, insomnia, anxiety, depression. Many do not discuss use with providers. Cardiovascular risks documented in younger populations but unstudied in seniors.

How They Did This

Narrative review synthesizing current literature on cannabis use trends, health considerations, and preclinical models relevant to older adult populations.

Why This Research Matters

The older adult population is growing and using cannabis at increasing rates, yet clinical trials and safety data are almost entirely from younger populations. Age-related changes in metabolism, cardiovascular health, and cognition create unique risk profiles.

The Bigger Picture

Cannabis sits in an interesting tension for older adults: it may help with common aging complaints (pain, sleep, appetite) while also carrying understudied risks for the cardiovascular and cognitive systems most vulnerable to aging.

What This Study Doesn't Tell Us

Narrative review without systematic methodology. Limited evidence base specific to older adults. Most existing data extrapolated from younger populations.

Questions This Raises

  • ?Does cannabis accelerate or slow cognitive decline in aging?
  • ?How do age-related changes in metabolism affect cannabis safety and dosing?
  • ?Why are many older adults not discussing cannabis use with their providers?

Trust & Context

Key Stat:
Fastest-growing demographic of cannabis users; most for medical purposes
Evidence Grade:
Moderate: narrative review identifying important knowledge gaps with limited direct evidence from older adult populations.
Study Age:
Published 2026.
Original Title:
Recent Trends in Cannabis Use in Adults Ages 60 Years and Older.
Published In:
Substance abuse and rehabilitation, 17, 560360 (2026)
Database ID:
RTHC-08659

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Summarizes existing research without a strict systematic method.

What do these levels mean? →

Frequently Asked Questions

Is cannabis safe for older adults?

The evidence is incomplete. Most cannabis safety data comes from younger populations, and age-related changes in cardiovascular health and cognition may create different risk profiles that need dedicated research.

Why do older adults use cannabis?

Most report medical purposes, particularly for pain, insomnia, anxiety, and depression. Many do not discuss their use with healthcare providers.

Read More on RethinkTHC

Cite This Study

RTHC-08659·https://rethinkthc.com/research/RTHC-08659

APA

Thayer, Rachel E; Anquillare, Elizabeth; Coromac-Medrano, Juliamaria; Hardin, Emily E; Hatcher, Kyle; Hermann, Greta E. (2026). Recent Trends in Cannabis Use in Adults Ages 60 Years and Older.. Substance abuse and rehabilitation, 17, 560360. https://doi.org/10.2147/SAR.S560360

MLA

Thayer, Rachel E, et al. "Recent Trends in Cannabis Use in Adults Ages 60 Years and Older.." Substance abuse and rehabilitation, 2026. https://doi.org/10.2147/SAR.S560360

RethinkTHC

RethinkTHC Research Database. "Recent Trends in Cannabis Use in Adults Ages 60 Years and Ol..." RTHC-08659. Retrieved from https://rethinkthc.com/research/thayer-2026-recent-trends-in-cannabis

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.