Mental health and GI relief were the top reasons pregnant women used cannabis, with over 84% citing multiple motivations

Analysis of surveillance data representing about 803,000 live births found mental health (82.8%) and gastrointestinal symptom relief (77.1%) were the most common motivations for prenatal cannabis use, with 84% of users citing two or more reasons.

Skelton, Kara R et al.·Journal of women's health (2002)·2026·Strong EvidenceCross-Sectional
RTHC-08631Cross SectionalStrong Evidence2026RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Cross-Sectional
Evidence
Strong Evidence
Sample
Not reported

What This Study Found

The most common motivations for prenatal cannabis use were mental health reasons (82.81%), gastrointestinal symptom relief (77.10%), pain relief (48.67%), fun or relaxation (40.18%), and chronic condition symptoms (26.31%). Most women (84.32%) reported multiple reasons, which was associated with daily or near-daily use.

Key Numbers

Data representing ~802,954 live births from 10 states. Mental health: 82.81%. GI symptoms: 77.10%. Pain: 48.67%. Fun/relaxation: 40.18%. Chronic conditions: 26.31%. Multiple reasons: 84.32%. Write-in responses: 54.90% cited pregnancy-related symptoms (nausea, appetite, sleep).

How They Did This

Analysis of 2017-2021 Pregnancy Risk Assessment Monitoring System (PRAMS) Marijuana Supplement data from 10 U.S. states. Weighted prevalence estimates of self-reported motivations for prenatal cannabis use were calculated and examined across sociodemographic characteristics and frequency of use.

Why This Research Matters

Understanding why pregnant women use cannabis is essential for developing effective clinical conversations. The finding that most users cite multiple overlapping reasons, particularly mental health and nausea, suggests they may be self-treating common pregnancy symptoms.

The Bigger Picture

This is one of the largest analyses of prenatal cannabis use motivations, drawn from a CDC surveillance system. The dominance of mental health and GI motivations suggests many women may be using cannabis as a substitute for medications they perceive as risky during pregnancy.

What This Study Doesn't Tell Us

Self-reported data from a surveillance system. Only 10 U.S. states participated in the marijuana supplement. Data from 2017-2021 may not reflect current patterns. Women who did not report cannabis use are excluded, likely underestimating prevalence.

Questions This Raises

  • ?Are women receiving adequate mental health support during pregnancy that might reduce cannabis use?
  • ?Do providers discuss safer alternatives for nausea and anxiety during prenatal visits?
  • ?How does frequency of use differ by motivation?

Trust & Context

Key Stat:
83% used cannabis for mental health; 77% for GI symptoms
Evidence Grade:
Strong: large population-based surveillance data from 10 U.S. states with weighted prevalence estimates representing over 800,000 births.
Study Age:
Published 2026. Data from 2017-2021 PRAMS.
Original Title:
Motivations for Cannabis Use During Pregnancy: An Analysis of 2017-2021 Pregnancy Assessment Monitoring System Data.
Published In:
Journal of women's health (2002), 15409996261424794 (2026)
Database ID:
RTHC-08631

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A snapshot of a population at one point in time.

What do these levels mean? →

Frequently Asked Questions

Why do pregnant women use cannabis?

The most common reasons were mental health (83%), gastrointestinal symptom relief like nausea (77%), pain (49%), and relaxation (40%). Over 84% cited multiple motivations.

Is prenatal cannabis use associated with daily use?

Women who reported multiple motivations for use were more likely to use cannabis daily or near-daily during pregnancy.

Read More on RethinkTHC

Cite This Study

RTHC-08631·https://rethinkthc.com/research/RTHC-08631

APA

Skelton, Kara R; Iobst, Stacey E; Benjamin-Neelon, Sara E. (2026). Motivations for Cannabis Use During Pregnancy: An Analysis of 2017-2021 Pregnancy Assessment Monitoring System Data.. Journal of women's health (2002), 15409996261424794. https://doi.org/10.1177/15409996261424794

MLA

Skelton, Kara R, et al. "Motivations for Cannabis Use During Pregnancy: An Analysis of 2017-2021 Pregnancy Assessment Monitoring System Data.." Journal of women's health (2002), 2026. https://doi.org/10.1177/15409996261424794

RethinkTHC

RethinkTHC Research Database. "Motivations for Cannabis Use During Pregnancy: An Analysis o..." RTHC-08631. Retrieved from https://rethinkthc.com/research/skelton-2026-motivations-for-cannabis-use

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.