A 36-year-old woman with CHS developed aortic blood clot and coronary artery disease
A 36-year-old woman with cannabinoid hyperemesis syndrome presented with chest pain and was found to have coronary artery disease and an aortic mural thrombus, requiring surgical intervention because CHS prevented antiplatelet therapy.
Quick Facts
What This Study Found
The patient had single-vessel coronary artery disease and an aortic mural thrombus. Standard treatment (antiplatelet therapy) was not possible because CHS caused inability to tolerate oral medication, necessitating coronary artery bypass and surgical thrombectomy instead.
Key Numbers
Age 36. Single-vessel coronary artery disease. Aortic mural thrombus. Required CABG and surgical thrombectomy due to CHS preventing antiplatelet therapy.
How They Did This
Single case report documenting a 36-year-old woman with CHS who presented with chest pain. Clinical management described including diagnostic workup and surgical intervention.
Why This Research Matters
This case illustrates how CHS can complicate treatment of other serious conditions. The persistent vomiting of CHS prevented oral antiplatelet therapy, forcing a more invasive surgical approach. It also raises questions about whether chronic cannabis use contributed to the cardiovascular pathology.
The Bigger Picture
Cardiovascular complications in cannabis users are increasingly reported but poorly understood. This case adds a unique angle: CHS not only represents a direct cannabis health risk but can also prevent standard medical treatment of other conditions.
What This Study Doesn't Tell Us
Single case. Cannot establish whether cannabis caused the cardiovascular pathology. The patient may have had other unmentioned risk factors.
Questions This Raises
- ?Did chronic cannabis use contribute to this patient's cardiovascular disease?
- ?How common are serious cardiovascular events in CHS patients?
- ?Should CHS patients receive cardiovascular screening?
Trust & Context
- Key Stat:
- CHS prevented standard antiplatelet therapy, forcing surgical intervention
- Evidence Grade:
- Single case report. Cannot establish causation but documents a clinically important complication.
- Study Age:
- 2021 case report.
- Original Title:
- Aortic Mural Thrombus and Acute Coronary Syndrome in a Patient With Cannabinoid Hyperemesis Syndrome.
- Published In:
- JACC. Case reports, 3(4), 694-696 (2021)
- Database ID:
- RTHC-03267
Evidence Hierarchy
Describes what happened to one person or a small group.
What do these levels mean? →Frequently Asked Questions
Can cannabis cause heart problems?
This case cannot prove causation, but a 36-year-old with CHS developing coronary artery disease and aortic thrombus is unusual for her age and raises the question of whether chronic cannabis use contributed.
How did CHS complicate treatment?
CHS caused persistent vomiting that prevented the patient from taking oral antiplatelet medications (standard treatment for coronary disease and blood clots), forcing surgical intervention instead.
Read More on RethinkTHC
- cannabis-cardiovascular-heart-risk-stroke
- cannabis-heart-cardiovascular-risk
- coughing-up-stuff-after-quitting-weed
- lung-recovery-after-quitting-smoking-weed
- lung-recovery-quitting-weed
- quitting-weed-female-hormones
- quitting-weed-weight-gain-loss-diet-appetite
- sex-after-quitting-weed
- weed-DUI-driving-impaired-cannabis-laws
- weed-acne-skin
- weed-fertility-sperm
- weed-gut-digestion-problems
- weed-heart-health
- weed-testosterone-levels
Cite This Study
https://rethinkthc.com/research/RTHC-03267APA
Labrada, Lyana; Patil, Aadhar; Lakhter, Vladimir; Minakata, Kenji; Islam, Sabrina. (2021). Aortic Mural Thrombus and Acute Coronary Syndrome in a Patient With Cannabinoid Hyperemesis Syndrome.. JACC. Case reports, 3(4), 694-696. https://doi.org/10.1016/j.jaccas.2021.02.020
MLA
Labrada, Lyana, et al. "Aortic Mural Thrombus and Acute Coronary Syndrome in a Patient With Cannabinoid Hyperemesis Syndrome.." JACC. Case reports, 2021. https://doi.org/10.1016/j.jaccas.2021.02.020
RethinkTHC
RethinkTHC Research Database. "Aortic Mural Thrombus and Acute Coronary Syndrome in a Patie..." RTHC-03267. Retrieved from https://rethinkthc.com/research/labrada-2021-aortic-mural-thrombus-and
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.