Medical marijuana laws were not associated with increased teen marijuana use across 46 states

Analyzing data from over 1 million high school students across 46 states from 1991-2015, researchers found no evidence that medical marijuana laws or dispensaries increased adolescent marijuana use.

Johnson, Julie K et al.·Substance abuse·2021·Strong EvidenceLongitudinal Cohort
RTHC-03227Longitudinal CohortStrong Evidence2021RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Longitudinal Cohort
Evidence
Strong Evidence
Sample
N=1,091,723

What This Study Found

States with enacted medical marijuana laws actually showed slightly lower adjusted odds of adolescent past-30-day marijuana use (OR=0.94, 95% CI: 0.89-0.99). No increase in heavy use (20+ days/month) was detected. Dispensary provisions were also not associated with higher adolescent use.

Key Numbers

1,091,723 students, 46 states, 1991-2015. MML states: OR=0.94 (95% CI: 0.89-0.99) for any past-30-day use. No significant effect on heavy use (20+ days). Dispensary provisions also not associated with increased use.

How They Did This

Natural-experimental design using state Youth Risk Behavior Survey (YRBS) data from 1,091,723 students in grades 9-12 across 46 states (1991-2015). Difference-in-difference estimates compared states before and after MML enactment. Multivariable logistic regression adjusted for state and year effects and student demographics.

Why This Research Matters

A primary concern about marijuana legalization is increased teen use. This study, one of the largest to examine the question, found no evidence for that concern across nearly 25 years of data, providing important evidence for the policy debate.

The Bigger Picture

These findings are consistent with a growing body of research suggesting that medical marijuana legalization does not measurably increase teen use. The slight negative association may reflect that states willing to enact MMLs also invest in youth prevention programs, though the study cannot confirm this.

What This Study Doesn't Tell Us

YRBS data is self-reported. Does not capture recreational legalization effects (only medical). Cannot account for all state-level confounders. 1991-2015 timeframe may not reflect more recent policy environments.

Questions This Raises

  • ?Does recreational legalization (vs. medical) show different effects on teen use?
  • ?What mediates the slightly protective association?
  • ?Would longer follow-up periods change the findings?

Trust & Context

Key Stat:
No increase in teen marijuana use after medical marijuana laws in 46 states
Evidence Grade:
Very large sample with quasi-experimental design across 25 years and 46 states. Strong for policy evaluation.
Study Age:
2021 study analyzing YRBS data from 1991-2015.
Original Title:
Medical marijuana laws (MMLs) and dispensary provisions not associated with higher odds of adolescent marijuana or heavy marijuana use: A 46 State Analysis, 1991-2015.
Published In:
Substance abuse, 42(4), 471-475 (2021)
Database ID:
RTHC-03227

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-ControlFollows or compares groups over time
This study
Cross-Sectional / Observational
Case Report / Animal Study

Follows a group of people over time to track how outcomes develop.

What do these levels mean? →

Frequently Asked Questions

Did medical marijuana laws increase teen marijuana use?

No. States with medical marijuana laws showed slightly lower odds of adolescent use (OR=0.94), and no increase in heavy use was detected across 46 states over 25 years.

What about marijuana dispensaries?

Operational dispensaries were also not associated with higher adolescent use, countering concerns that physical access points would increase teen exposure.

Read More on RethinkTHC

Cite This Study

RTHC-03227·https://rethinkthc.com/research/RTHC-03227

APA

Johnson, Julie K; Johnson, Renee M; Hodgkin, Dominic; Jones, Abenaa A; Kritikos, Alexandra; Doonan, Samantha M; Harris, Sion K. (2021). Medical marijuana laws (MMLs) and dispensary provisions not associated with higher odds of adolescent marijuana or heavy marijuana use: A 46 State Analysis, 1991-2015.. Substance abuse, 42(4), 471-475. https://doi.org/10.1080/08897077.2021.1900986

MLA

Johnson, Julie K, et al. "Medical marijuana laws (MMLs) and dispensary provisions not associated with higher odds of adolescent marijuana or heavy marijuana use: A 46 State Analysis, 1991-2015.." Substance abuse, 2021. https://doi.org/10.1080/08897077.2021.1900986

RethinkTHC

RethinkTHC Research Database. "Medical marijuana laws (MMLs) and dispensary provisions not ..." RTHC-03227. Retrieved from https://rethinkthc.com/research/johnson-2021-medical-marijuana-laws-mmls

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.