States with Legal Cannabis Saw More Asthma Hospitalizations

States with medical cannabis dispensaries saw 14% more asthma hospitalizations, and states with recreational cannabis saw 20% more, compared to states without these policies.

Jayawardhana, Jayani et al.·Health services research·2025·Moderate Evidencequasi-experimental
RTHC-06743Quasi ExperimentalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
quasi-experimental
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

States with medical cannabis dispensaries experienced a 14.12% increase in inpatient asthma visits compared to states without. States with recreational cannabis legalization saw a 20.45% increase. These increases were primarily driven by Medicare and privately insured populations. Simple passage of medical cannabis laws or home cultivation allowances did not significantly affect asthma hospitalizations.

Key Numbers

Medical cannabis dispensaries: +14.12% asthma hospitalizations (2.14 per 100k; 95% CI: 0.74-3.53; p<0.01). Recreational cannabis: +20.45% increase (3.08 per 100k; 95% CI: 1.47-4.69; p<0.001). Effects larger in Medicare populations. No significant effects from law passage or home cultivation alone.

How They Did This

Difference-in-differences regression analysis using state-level quarterly inpatient visit data from the HCUP Fast Stats database (2005-2017). Compared asthma hospitalizations in 38 states before and after implementation of four types of cannabis laws, with analyses stratified by payer type.

Why This Research Matters

While cannabis legalization debates focus on addiction and mental health, this study highlights an underappreciated respiratory consequence that carries substantial healthcare costs.

The Bigger Picture

The finding that actual cannabis access (dispensaries, retail) drives asthma hospitalizations while law passage alone does not suggests the mechanism is increased cannabis smoke exposure rather than a legal status effect.

What This Study Doesn't Tell Us

Ecological study cannot confirm individual-level cannabis use caused asthma hospitalizations. Other state-level changes may confound results. 2005-2017 timeframe precedes widespread vaping. Cannot distinguish between patient cannabis use and secondhand exposure.

Questions This Raises

  • ?Would promoting non-smoked cannabis products reduce the asthma hospitalization impact?
  • ?How much of the increase is from direct use versus secondhand cannabis smoke exposure?

Trust & Context

Key Stat:
20.45% increase in asthma hospitalizations in states with legal recreational cannabis
Evidence Grade:
Strong quasi-experimental design with appropriate controls, but ecological data cannot confirm individual-level causation.
Study Age:
2025 publication with 2005-2017 data.
Original Title:
Impact of medical and recreational cannabis laws on inpatient visits for asthma.
Published In:
Health services research, 60(3), e14427 (2025)
Database ID:
RTHC-06743

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Read More on RethinkTHC

Cite This Study

RTHC-06743·https://rethinkthc.com/research/RTHC-06743

APA

Jayawardhana, Jayani; Fernandez, Jose. (2025). Impact of medical and recreational cannabis laws on inpatient visits for asthma.. Health services research, 60(3), e14427. https://doi.org/10.1111/1475-6773.14427

MLA

Jayawardhana, Jayani, et al. "Impact of medical and recreational cannabis laws on inpatient visits for asthma.." Health services research, 2025. https://doi.org/10.1111/1475-6773.14427

RethinkTHC

RethinkTHC Research Database. "Impact of medical and recreational cannabis laws on inpatien..." RTHC-06743. Retrieved from https://rethinkthc.com/research/jayawardhana-2025-impact-of-medical-and

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.