Cannabis legalization in Canada did not increase self-harm rates in Ontario or Alberta

An interrupted time series analysis found no significant change in emergency department visits or hospitalizations for intentional self-harm in Ontario or Alberta following cannabis legalization in Canada.

Cusimano, Michael D et al.·Health promotion and chronic disease prevention in Canada : research·2023·Moderate EvidenceObservational
RTHC-04478ObservationalModerate Evidence2023RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Using population-based data from January/April 2010 to February 2020, cannabis legalization and regulation in Canada was not significantly associated with changes in ED visits for intentional self-harm in Ontario (level=0.58, 95% CI -1.14 to 2.31) or Alberta (level=-0.06, 95% CI -2.25 to 2.12). Hospitalizations for self-harm also remained unchanged in both provinces.

Key Numbers

Ontario ED visits: level 0.58 (95% CI -1.14 to 2.31); Alberta ED visits: level -0.06 (95% CI -2.25 to 2.12); Ontario hospitalizations: level -0.14 (95% CI -0.48 to 0.20); Alberta hospitalizations: level -0.41 (95% CI -1.03 to 0.21); none significant

How They Did This

Interrupted time series analysis of population-based rates of ED visits and hospitalizations for intentional self-harm (ICD-10 codes X60-X84, R45.8) per 100,000 in Ontario and Alberta from 2010-2020 using the National Ambulatory Care Reporting System and Discharge Abstract Database.

Why This Research Matters

Concerns about cannabis legalization increasing mental health crises, including self-harm, have been used to argue against legalization policies. This two-province analysis finds no evidence supporting that concern.

The Bigger Picture

While cannabis use has been associated with suicidal ideation in individual-level studies, population-level legalization does not appear to translate into increased self-harm healthcare utilization.

What This Study Doesn't Tell Us

Only two provinces analyzed (pre-2020 to avoid COVID confounding). Population-level data cannot identify individual-level effects. Relatively short post-legalization period (October 2018 to February 2020). ICD coding may miss some self-harm presentations.

Questions This Raises

  • ?Would a longer post-legalization follow-up period reveal delayed effects?
  • ?Are there subpopulations where self-harm did increase that are masked by overall trends?

Trust & Context

Key Stat:
No significant change in self-harm rates after cannabis legalization in two provinces
Evidence Grade:
Population-based interrupted time series using standardized health system data, though short post-legalization period and two-province analysis limit conclusions.
Study Age:
Published 2023 using 2010-2020 data
Original Title:
An interrupted time series evaluation of the effect of cannabis legalization on intentional self-harm in two Canadian provinces: Ontario and Alberta.
Published In:
Health promotion and chronic disease prevention in Canada : research, policy and practice, 43(9), 403-408 (2023)
Database ID:
RTHC-04478

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

Did cannabis legalization increase self-harm in Canada?

No. This analysis of Ontario and Alberta found no significant change in emergency department visits or hospitalizations for intentional self-harm after cannabis was legalized in October 2018.

Does this mean cannabis doesn't affect mental health?

Not necessarily. Individual-level studies have linked cannabis to suicidal ideation, but this population-level analysis shows that legalization as a policy did not increase self-harm healthcare utilization in these two provinces.

Read More on RethinkTHC

Cite This Study

RTHC-04478·https://rethinkthc.com/research/RTHC-04478

APA

Cusimano, Michael D; Carpino, Melissa; Walker, Madison; Saarela, Olli; Mann, Robert. (2023). An interrupted time series evaluation of the effect of cannabis legalization on intentional self-harm in two Canadian provinces: Ontario and Alberta.. Health promotion and chronic disease prevention in Canada : research, policy and practice, 43(9), 403-408. https://doi.org/10.24095/hpcdp.43.9.02

MLA

Cusimano, Michael D, et al. "An interrupted time series evaluation of the effect of cannabis legalization on intentional self-harm in two Canadian provinces: Ontario and Alberta.." Health promotion and chronic disease prevention in Canada : research, 2023. https://doi.org/10.24095/hpcdp.43.9.02

RethinkTHC

RethinkTHC Research Database. "An interrupted time series evaluation of the effect of canna..." RTHC-04478. Retrieved from https://rethinkthc.com/research/cusimano-2023-an-interrupted-time-series

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.