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Study breakdown

Medical cannabis laws had minimal effect on pharmaceutical marketing to physicians

ObservationalModerate evidence
The takeaway

Analysis of pharmaceutical detailing records from 2014-2018 found only weak evidence that medical cannabis laws reduced drug company marketing to physicians, with any effects small and delayed.

Health economists, pharmaceutical industry analysts, and cannabis policy researchers.

Medical cannabis laws produced only weak, economically small effects on pharma marketing

What the researchers found

Medical cannabis law enactment was associated with weak evidence of small, delayed reductions in pharmaceutical detailing for substitute prescription drugs and opioids. Effects were slightly more pronounced among smaller pharmaceutical firms. However, the magnitudes were economically small, likely because only a small percentage of doctors actively recommend cannabis for medical treatment.

Why it matters

If medical cannabis truly substitutes for prescription drugs, pharmaceutical companies should reduce marketing in response. The finding of minimal marketing response suggests either that cannabis substitution is limited in practice or that pharma companies do not perceive cannabis as a serious market threat.

The numbers in context

Data from 2014-2018 county-level detailing records. Weak evidence of reduced detailing for substitute drugs and opioids. Larger effects in smaller firms. Magnitudes economically small.

How the study worked

Exploited geographic and temporal variation in medical cannabis laws across US states. Used office detailing records from 2014-2018 aggregated to the county level. Examined changes in direct-to-physician marketing by pharmaceutical firms following MCL enactment.

What this study cannot tell us

Observational with county-level aggregation. Cannot directly measure prescription substitution. Detailing records may not capture all marketing channels. 2014-2018 period captures early MCL effects only.

How to read the evidence

Novel dataset with appropriate econometric methods. Limited by indirect measurement of cannabis substitution effects.

When this study was published

2021 study using 2014-2018 pharmaceutical detailing data.

The bigger picture

The muted pharmaceutical marketing response to cannabis laws contrasts with survey data showing patients self-reporting large-scale prescription substitution. This disconnect suggests that at the population level, medical cannabis may not yet be shifting prescription drug markets as dramatically as individual surveys suggest.

Questions still open

  • Would recreational legalization produce larger marketing responses? Are pharmaceutical companies underestimating cannabis competition? Would longer follow-up periods reveal larger effects?

Common questions

Did medical cannabis laws change how drug companies market to doctors?
Barely. There was weak evidence of small, delayed reductions in marketing for drugs that cannabis could substitute for, but the effects were economically small.
Why was the response so small?
The authors suggest it is because only a small percentage of physicians actively recommend cannabis for medical treatment, so pharmaceutical companies do not yet see it as a significant market competitor.

Read the original research

The effect of medical cannabis laws on pharmaceutical marketing to physicians.

Health economics, 30(10), 2409-2436

Citation

Lebesmuehlbacher, Thomas; Smith, Rhet A. (2021). The effect of medical cannabis laws on pharmaceutical marketing to physicians.. Health economics, 30(10), 2409-2436. https://doi.org/10.1002/hec.4380