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Global Meta-Analysis: 29% of Medical Students Have Tried Cannabis at Least Once

Systematic Review And Meta AnalysisModerate evidence
The takeaway

A meta-analysis of 109 studies across 32 countries found 29.2% lifetime cannabis prevalence among medical students, with rates declining from the 1970s through the 2000s before rebounding in the 2020s.

Medical educators, public health researchers, medical students

29.2% lifetime prevalence across 62,444 medical students globally

What the researchers found

Across 62,444 medical students from 32 countries, lifetime cannabis prevalence was 29.2%, past-year 20.5%, past-month 9.2%, and past-week 5.1%. Prevalence declined from 38.4% in the 1970s to 18.1% in the 2000s, then rebounded to 30.4% in the 2020s, driven by increases in Latin America, Asia, and Africa.

Why it matters

Medical students represent a population that will eventually counsel patients about cannabis. Understanding their own use patterns and how those have shifted over five decades provides context for how the medical profession interfaces with cannabis culture.

The numbers in context

109 studies; 62,444 participants; 32 countries; lifetime prevalence 29.2%; Anglo-Saxon America highest at 59.7%; Asia lowest at 11.5%; 2020s rebound to 30.4%.

How the study worked

Systematic review and meta-analysis of 109 observational studies published 1971-2025, identified from six databases. Data pooled using random-effects models with subgroup analyses by gender, study cycle, school type, decade, and world region.

What this study cannot tell us

Heterogeneity across 109 studies spanning five decades and 32 countries. Self-reported use subject to underreporting, especially in regions with strict prohibition. Different survey instruments and definitions of use across studies.

How to read the evidence

Large meta-analysis spanning decades and continents, though limited by heterogeneity in underlying studies and self-report bias.

When this study was published

2025 publication covering studies from 1971-2025

The bigger picture

The rebound in medical student cannabis use during the 2020s, particularly in regions where legalization or decriminalization is expanding, parallels broader population trends. The wide regional variation (11.5% in Asia vs. 59.7% in Anglo-Saxon America) highlights how cultural and legal contexts shape use patterns.

Questions still open

  • Does personal cannabis experience among medical students influence their clinical attitudes toward medical cannabis?
  • What is driving the 2020s rebound in medical student cannabis use in Latin America, Asia, and Africa?

Common questions

How common is cannabis use among medical students?
Globally, about 29% of medical students have tried cannabis at least once, 20.5% used in the past year, and 9.2% in the past month, based on a meta-analysis of 109 studies across 32 countries.
Is cannabis use increasing among medical students?
After declining from 38.4% in the 1970s to 18.1% in the 2000s, lifetime prevalence rebounded to 30.4% in the 2020s, with increases driven by Latin America, Asia, and Africa.

Read the original research

Global temporal and regional trends in cannabis use among medical students: A systematic review and meta-analysis.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

Citation

Karpovisch, Eduardo; Alves, Gabriel Grando; Folgierini, Vicente Fichbein; Braun, Luiza Elizabete; Porto, Ighor Miron; Hoffmann, Mauricio Scopel; Pacheco, João Pedro Gonçalves. (2025). Global temporal and regional trends in cannabis use among medical students: A systematic review and meta-analysis.. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). https://doi.org/10.47626/1516-4446-2025-4286