Cannabis and Vaping Rose After Legalization, But Cigarette Use Did Not
Five years after recreational cannabis legalization, cannabis use increased by 3.28 percentage points and e-cigarette use by 1.39 points, while cigarette use did not significantly change.
Quick Facts
What This Study Found
Using difference-in-differences analysis of 171,257 observations from 55,406 individuals, recreational cannabis legalization was associated with a 3.28 percentage point increase in cannabis use and 1.39 percentage point increase in ENDS use compared to control states. Cigarette use did not significantly change (-0.99 points). Cannabis use increased more after retail outlets opened (3.74 points) than before (1.17 points).
Key Numbers
171,257 observations from 55,406 individuals (50.9% female, mean age 37.97). Cannabis use: +3.28 pp (95% CI: 2.29-4.27). ENDS use: +1.39 pp (95% CI: 0.44-2.35). Cigarettes: -0.99 pp (95% CI: -2.25-0.27, not significant). Post-retail cannabis increase: +3.74 pp vs pre-retail +1.17 pp.
How They Did This
Difference-in-differences analysis of the nationally representative Population Assessment of Tobacco and Health (PATH) longitudinal cohort study (2013-2022), comparing states with recreational cannabis legalization to control states over 5 years.
Why This Research Matters
This is one of the first studies with enough follow-up to show longer-term effects of cannabis legalization on both cannabis and tobacco product use, using a rigorous causal inference design.
The Bigger Picture
The finding that legalization increases cannabis use but not cigarette use addresses a key policy concern. The unexpected increase in e-cigarette use suggests cross-product effects that regulators should monitor, potentially driven by vaping hardware crossover.
What This Study Doesn't Tell Us
Observational design despite difference-in-differences approach. State-level variation in implementation complicates uniform analysis. Self-reported use. Does not capture frequency or quantity changes within users. Cannot identify which individuals are new users versus increased users.
Questions This Raises
- ?Why did e-cigarette use increase alongside cannabis legalization?
- ?Does the post-retail acceleration of cannabis use plateau or continue climbing beyond 5 years?
Trust & Context
- Key Stat:
- Cannabis use rose 3.28 percentage points after legalization, accelerating to 3.74 points after retail outlets opened
- Evidence Grade:
- Large nationally representative longitudinal cohort with difference-in-differences design provides strong causal evidence. Published in JAMA Network Open.
- Study Age:
- 2025 JAMA Network Open publication with 2013-2022 data.
- Original Title:
- Use of Tobacco and Cannabis Following State-Level Cannabis Legalization.
- Published In:
- JAMA network open, 8(7), e2520093 (2025)
- Authors:
- Hyatt, Andrew S(2), Overhage, Lindsay, Cook, Benjamin Lê(3)
- Database ID:
- RTHC-06706
Evidence Hierarchy
Read More on RethinkTHC
Cite This Study
https://rethinkthc.com/research/RTHC-06706APA
Hyatt, Andrew S; Overhage, Lindsay; Cook, Benjamin Lê. (2025). Use of Tobacco and Cannabis Following State-Level Cannabis Legalization.. JAMA network open, 8(7), e2520093. https://doi.org/10.1001/jamanetworkopen.2025.20093
MLA
Hyatt, Andrew S, et al. "Use of Tobacco and Cannabis Following State-Level Cannabis Legalization.." JAMA network open, 2025. https://doi.org/10.1001/jamanetworkopen.2025.20093
RethinkTHC
RethinkTHC Research Database. "Use of Tobacco and Cannabis Following State-Level Cannabis L..." RTHC-06706. Retrieved from https://rethinkthc.com/research/hyatt-2025-use-of-tobacco-and
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.