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Study breakdown

Cannabis Use During Pregnancy: What the Research Shows

evidence
The takeaway

Cannabis use during pregnancy is associated with increased risk of preterm birth, NICU admission, low birth weight, and small-for-gestational-age infants.

Obstetricians, midwives, prenatal counselors, and pregnant women considering cannabis use.

Rising prenatal use

associated with preterm birth, NICU admission, low birth weight, and small-for-gestational-age infants

What the researchers found

Available studies support an association between prenatal cannabis use and increased risk of preterm birth, neonatal intensive care unit admission, low birth weight, and small-for-gestational-age infants.

Why it matters

Prenatal cannabis use is rising and poses documented risks to maternal and fetal health, yet many pregnant women are unaware of these risks or receive conflicting information.

The numbers in context

Not quantified in abstract; review summarizes associations with preterm birth, NICU admission, low birth weight, and small-for-gestational-age outcomes across available studies.

How the study worked

Literature review searching PubMed, Cochrane Library, and Google Scholar using terms related to cannabis, cannabinoids, pregnancy, and lactation outcomes.

Who was studied

Pregnant and lactating women using cannabis (across reviewed studies).

What this study cannot tell us

Review rather than systematic review or meta-analysis. Underlying studies may have confounding by tobacco, alcohol, or other substance co-use. Self-reported cannabis use may be underestimated.

How to read the evidence

Narrative review summarizing observational evidence; associations are consistent but confounding cannot be fully excluded.

When this study was published

Recent review reflecting current literature on cannabis and pregnancy.

The bigger picture

As cannabis becomes more accessible and prenatal use rises, healthcare providers need clear guidance on counseling patients about the established risks of cannabis use during pregnancy.

Replication

Narrative review of consistent findings across multiple observational studies.

Funding

Not specified in abstract

Conflicts of interest

Not specified in abstract

Questions still open

  • What mechanisms link cannabis to adverse birth outcomes?
  • Are specific cannabinoids (THC vs. CBD) differentially harmful during pregnancy?

Read the original research

Cannabis and Pregnancy: A Review.

Obstetrical & gynecological survey, 78(7), 411-428

Citation

Hayer, Sarena; Mandelbaum, Ava D; Watch, Lester; Ryan, Kimberly S; Hedges, Madeline A; Manuzak, Jennifer A; Easley, Charles A; Schust, Danny J; Lo, Jamie O. (2023). Cannabis and Pregnancy: A Review.. Obstetrical & gynecological survey, 78(7), 411-428. https://doi.org/10.1097/OGX.0000000000001159