Research summaries that bring together findings, disagreements, and open questions.
The research base for medical cannabis & drug interactions includes 1691 peer-reviewed studies spanning 1975–2026. Of these, 142 provide strong evidence, including 36 meta-analyses and 141 randomized controlled trials. Key findings with str…
The research base for is weed addictive includes 1380 peer-reviewed studies spanning 1981–2026. Of these, 219 provide strong evidence, including 28 meta-analyses and 99 randomized controlled trials. Key findings with strong support include:…
The research base for cannabis and your brain includes 1316 peer-reviewed studies spanning 1975–2026. Of these, 73 provide strong evidence, including 16 meta-analyses and 70 randomized controlled trials. Key findings with strong support inc…
The research base for parents guide to cannabis includes 1291 peer-reviewed studies spanning 1976–2026. Of these, 203 provide strong evidence, including 23 meta-analyses and 67 randomized controlled trials. Key findings with strong support …
The research base for cbd research includes 1137 peer-reviewed studies spanning 1984–2026. Of these, 116 provide strong evidence, including 23 meta-analyses and 160 randomized controlled trials. Key findings with strong support include: met…
The research base for harm reduction & smart use includes 844 peer-reviewed studies spanning 1975–2026. Of these, 103 provide strong evidence, including 16 meta-analyses and 74 randomized controlled trials. Key findings with strong support …
The research base for cannabis and mental health includes 840 peer-reviewed studies spanning 1996–2026. Of these, 144 provide strong evidence, including 21 meta-analyses and 37 randomized controlled trials. Key findings with strong support …
The research base for cannabis and cognition includes 705 peer-reviewed studies spanning 1975–2026. Of these, 82 provide strong evidence, including 16 meta-analyses and 89 randomized controlled trials. Key findings with strong support inclu…
The research base for cannabis and pain includes 656 peer-reviewed studies spanning 1981–2026. Of these, 66 provide strong evidence, including 12 meta-analyses and 47 randomized controlled trials. Key findings with strong support include: m…
The research base for cannabis law & your rights includes 647 peer-reviewed studies spanning 1981–2026. Of these, 141 provide strong evidence, including 5 meta-analyses and 15 randomized controlled trials. Key findings with strong support i…
The research base for cannabis and psychosis includes 528 peer-reviewed studies spanning 1999–2026. Of these, 97 provide strong evidence, including 19 meta-analyses and 36 randomized controlled trials. Key findings with strong support inclu…
The research base for cannabis and pregnancy includes 416 peer-reviewed studies spanning 1986–2026. Of these, 49 provide strong evidence, including 9 meta-analyses and 0 randomized controlled trials. Key findings with strong support include…
The research base for cannabis and inflammation includes 370 peer-reviewed studies spanning 1975–2026. Of these, 9 provide strong evidence, including 5 meta-analyses and 13 randomized controlled trials. Key findings with strong support incl…
The research base for cannabis effects & experience includes 328 peer-reviewed studies spanning 1975–2026. Of these, 44 provide strong evidence, including 5 meta-analyses and 41 randomized controlled trials. Key findings with strong support…
The research base for cannabis and driving includes 251 peer-reviewed studies spanning 1976–2026. Of these, 45 provide strong evidence, including 6 meta-analyses and 46 randomized controlled trials. Key findings with strong support include:…
The research base for cannabis and cancer includes 242 peer-reviewed studies spanning 1975–2026. Of these, 13 provide strong evidence, including 5 meta-analyses and 10 randomized controlled trials. Key findings with strong support include: …
The relationship between cannabis and anxiety is defined by a fundamental paradox: low-dose THC reliably reduces acute anxiety through CB1 receptor activation in the amygdala, while higher doses and chronic use are associated with increased…
The research base for how to quit smoking weed includes 224 peer-reviewed studies spanning 1994–2026. Of these, 25 provide strong evidence, including 5 meta-analyses and 59 randomized controlled trials. Key findings with strong support incl…
The research base for benefits of quitting weed includes 221 peer-reviewed studies spanning 1994–2026. Of these, 25 provide strong evidence, including 5 meta-analyses and 59 randomized controlled trials. Key findings with strong support inc…
The research base for cannabis and your body includes 213 peer-reviewed studies spanning 1975–2026. Of these, 21 provide strong evidence, including 7 meta-analyses and 7 randomized controlled trials. Key findings with strong support include…
The research base for sex differences in cannabis includes 212 peer-reviewed studies spanning 2000–2026. Of these, 16 provide strong evidence, including 3 meta-analyses and 9 randomized controlled trials. Key findings with strong support in…
The research base for cannabis and epilepsy includes 210 peer-reviewed studies spanning 2003–2026. Of these, 50 provide strong evidence, including 11 meta-analyses and 4 randomized controlled trials. Key findings with strong support include…
The research base for cannabis genetics includes 196 peer-reviewed studies spanning 1998–2026. Of these, 38 provide strong evidence, including 7 meta-analyses and 9 randomized controlled trials. Key findings with strong support include: met…
The research base for cannabis and depression includes 193 peer-reviewed studies spanning 2001–2026. Of these, 30 provide strong evidence, including 7 meta-analyses and 6 randomized controlled trials. Key findings with strong support includ…
The research base for cannabis products & consumption includes 180 peer-reviewed studies spanning 2009–2026. Of these, 5 provide strong evidence, including 0 meta-analyses and 4 randomized controlled trials. Key findings with strong support…
The research base for synthetic cannabinoids includes 180 peer-reviewed studies spanning 2009–2026. Of these, 5 provide strong evidence, including 0 meta-analyses and 4 randomized controlled trials. Key findings with strong support include:…
Cannabis withdrawal is real, clinically recognized, and affects roughly half of regular users who stop. The first meta-analysis on this question (Bahji et al., 2020) pooled 23 studies with over 27,000 participants and found a prevalence of …
The research base for cannabis and drug interactions includes 160 peer-reviewed studies spanning 1976–2026. Of these, 18 provide strong evidence, including 4 meta-analyses and 14 randomized controlled trials. Key findings with strong suppor…
The research base for cannabis and potency includes 152 peer-reviewed studies spanning 2000–2026. Of these, 27 provide strong evidence, including 1 meta-analyses and 16 randomized controlled trials. Key findings with strong support include:…
Cannabis is one of the most commonly self-prescribed sleep aids in the world. In Canada, 16% of adults report using it for sleep — more than use prescription sleep medications. In perimenopausal women, the figure is 67%. The appeal is strai…
The research base for cannabis and appetite includes 142 peer-reviewed studies spanning 1997–2026. Of these, 3 provide strong evidence, including 1 meta-analyses and 6 randomized controlled trials. Key findings with strong support include: …
The research base for cannabis and respiratory health includes 135 peer-reviewed studies spanning 1975–2026. Of these, 12 provide strong evidence, including 1 meta-analyses and 2 randomized controlled trials. Key findings with strong suppor…
The research base for cannabis and dopamine includes 129 peer-reviewed studies spanning 1992–2026. Of these, 5 provide strong evidence, including 0 meta-analyses and 11 randomized controlled trials. Key findings with strong support include:…
The research base for cannabis and seniors includes 106 peer-reviewed studies spanning 1981–2026. Of these, 12 provide strong evidence, including 1 meta-analyses and 6 randomized controlled trials. Key findings with strong support include: …
The research base for thc research includes 103 peer-reviewed studies spanning 2024–2026. Of these, 11 provide strong evidence, including 2 meta-analyses and 5 randomized controlled trials. Key findings with strong support include: meta-ana…
The research base for cannabis and ptsd includes 102 peer-reviewed studies spanning 2006–2026. Of these, 9 provide strong evidence, including 3 meta-analyses and 1 randomized controlled trials. Key findings with strong support include: a la…
The research base for cannabis health risks includes 84 peer-reviewed studies spanning 2025–2026. Of these, 7 provide strong evidence, including 4 meta-analyses and 0 randomized controlled trials. Key findings with strong support include: m…
The research base for cannabis and performance includes 77 peer-reviewed studies spanning 2001–2026. Of these, 7 provide strong evidence, including 1 meta-analyses and 7 randomized controlled trials. Key findings with strong support include…
The research base for cannabis policy includes 69 peer-reviewed studies spanning 2024–2026. Of these, 13 provide strong evidence, including 0 meta-analyses and 0 randomized controlled trials. Key findings with strong support include: analys…
The research base for endocannabinoid system includes 53 peer-reviewed studies spanning 2024–2026. including 0 meta-analyses and 0 randomized controlled trials. However, several findings remain debated, and the evidence is not uniform acros…
The research base for cannabis and substance use includes 47 peer-reviewed studies spanning 2025–2026. Of these, 7 provide strong evidence, including 0 meta-analyses and 0 randomized controlled trials. Key findings with strong support inclu…
The research base for cannabis and exercise includes 46 peer-reviewed studies spanning 2012–2026. Of these, 3 provide strong evidence, including 1 meta-analyses and 6 randomized controlled trials. Key findings with strong support include: r…
The research base for cannabis and adolescents includes 44 peer-reviewed studies spanning 2025–2026. Of these, 20 provide strong evidence, including 0 meta-analyses and 0 randomized controlled trials. Key findings with strong support includ…
The research base for cannabis public health includes 38 peer-reviewed studies spanning 2025–2026. Of these, 6 provide strong evidence, including 0 meta-analyses and 0 randomized controlled trials. Key findings with strong support include: …
The research base for cannabis and alcohol includes 35 peer-reviewed studies spanning 2024–2026. Of these, 8 provide strong evidence, including 0 meta-analyses and 0 randomized controlled trials. Key findings with strong support include: an…
The research base for cannabis and the workplace includes 31 peer-reviewed studies spanning 2001–2026. Of these, 4 provide strong evidence, including 0 meta-analyses and 1 randomized controlled trials. Key findings with strong support inclu…
The research base for cannabis use disorder includes 30 peer-reviewed studies spanning 2025–2026. Of these, 10 provide strong evidence, including 0 meta-analyses and 0 randomized controlled trials. Key findings with strong support include: …
Research on neuroprotection and cannabis is limited — only 24 studies are available in the literature (2025–2026). Conclusions should be considered preliminary and may evolve as more research is conducted. However, several findings remain d…
Research on cannabis and tobacco is limited — only 23 studies are available in the literature (2022–2026). Conclusions should be considered preliminary and may evolve as more research is conducted. Key findings with strong support include: …
Research on cannabis pharmacology is limited — only 22 studies are available in the literature (2025–2026). Conclusions should be considered preliminary and may evolve as more research is conducted. Key findings with strong support include:…
Research on cannabis and the gut is limited — only 16 studies are available in the literature (2024–2026). Conclusions should be considered preliminary and may evolve as more research is conducted. Key findings with strong support include: …
Research on cannabis and vaping is limited — only 15 studies are available in the literature (2024–2026). Conclusions should be considered preliminary and may evolve as more research is conducted. Key findings with strong support include: a…