A smartphone app showed early promise for reducing cannabis-impaired driving among young Canadians

The "High Alert" smartphone intervention was well received by young cannabis users and showed preliminary efficacy in reducing driving after cannabis co-use, though recruitment barriers and high attrition posed challenges.

Colonna, Robert et al.·PloS one·2025·Preliminary EvidencePilot Study
RTHC-06246Pilot StudyPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Pilot Study
Evidence
Preliminary Evidence
Sample
Not reported

What This Study Found

High Alert, a digital smartphone intervention for youth DUIC, was positively received by participants and showed preliminary efficacy in reducing driving after cannabis co-use compared to a no-contact control. However, implementation challenges including online bot activity, recruitment barriers, and high attrition rates were significant.

Key Numbers

Most participants were willing to engage with the app and recommend it to peers. Content and delivery ratings exceeded those of static infographics. Preliminary efficacy was shown for reducing driving after cannabis co-use vs. no-contact group.

How They Did This

Pilot randomized controlled trial comparing High Alert (smartphone intervention) to an active control (DUIC infographics) and a passive control (no contact), evaluated using the six-step Intervention Mapping framework including formative, process, outcome, and acceptability evaluations.

Why This Research Matters

Cannabis-impaired driving among youth is a growing concern in jurisdictions with legalized cannabis. Digital interventions are scalable, but this study highlights the practical challenges of deploying them to high-risk young populations.

The Bigger Picture

This study demonstrates both the potential and the pitfalls of digital health interventions for substance-related driving behaviors. The recruitment and retention challenges reported are common across digital intervention research with young adults.

What This Study Doesn't Tell Us

Pilot study with small sample size. High attrition limits generalizability. Bot activity during online recruitment complicated data quality. Active control group may have also received benefit from infographic exposure.

Questions This Raises

  • ?Can High Alert be scaled effectively given the recruitment and retention challenges?
  • ?Would combining the app with in-person touchpoints improve engagement?

Trust & Context

Key Stat:
Preliminary efficacy for reducing co-use driving
Evidence Grade:
Pilot RCT with small sample, high attrition, and implementation challenges. Provides proof of concept but not definitive efficacy evidence.
Study Age:
2025 publication
Original Title:
Using intervention mapping to evaluate 'High-Alert,' a brief smartphone intervention to reduce youth cannabis-impaired driving.
Published In:
PloS one, 20(8), e0329383 (2025)
Database ID:
RTHC-06246

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

A small preliminary study to test whether a larger study is feasible.

What do these levels mean? →

Frequently Asked Questions

What is High Alert?

High Alert is a brief digital smartphone intervention designed to reduce cannabis-impaired driving among high-risk Canadian youth, developed using the Intervention Mapping framework.

Did the app actually reduce cannabis-impaired driving?

There was preliminary evidence of reduced driving after cannabis co-use compared to the no-contact group, but high attrition and small sample size mean these results need confirmation in a larger trial.

Read More on RethinkTHC

Cite This Study

RTHC-06246·https://rethinkthc.com/research/RTHC-06246

APA

Colonna, Robert; Tucker, Patricia; Mandich, Angela; Alvarez, Liliana. (2025). Using intervention mapping to evaluate 'High-Alert,' a brief smartphone intervention to reduce youth cannabis-impaired driving.. PloS one, 20(8), e0329383. https://doi.org/10.1371/journal.pone.0329383

MLA

Colonna, Robert, et al. "Using intervention mapping to evaluate 'High-Alert,' a brief smartphone intervention to reduce youth cannabis-impaired driving.." PloS one, 2025. https://doi.org/10.1371/journal.pone.0329383

RethinkTHC

RethinkTHC Research Database. "Using intervention mapping to evaluate 'High-Alert,' a brief..." RTHC-06246. Retrieved from https://rethinkthc.com/research/colonna-2025-using-intervention-mapping-to

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.