Using Alcohol and Cannabis Together Changes How People Judge Their Driving Ability

In 88 adults who regularly co-use alcohol and cannabis, simultaneous use increased perceived driving impairment but paradoxically also increased willingness to drive compared to alcohol alone.

Wycoff, Andrea M et al.·Experimental and clinical psychopharmacology·2025·Moderate EvidenceObservational
RTHC-07980ObservationalModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Observational
Evidence
Moderate Evidence
Sample
N=88

What This Study Found

Simultaneous alcohol and cannabis use increased perceived driving impairment, yet participants were 3.7x more willing to drive within an hour compared to alcohol-only use, suggesting cannabis may attenuate alcohol's deterrent effect on driving decisions.

Key Numbers

88 adults, 14 days of EMA, average 5.14 surveys/day. Simultaneous users were 3.69x more willing to drive within 1 hour (95% CI: 2.15-6.34) compared to alcohol-only use.

How They Did This

Ecological momentary assessment over 14 days with 88 adults (ages 18-44) who co-use alcohol and cannabis at least twice weekly, completing an average of 5.14 surveys per day on substance use, perceived impairment, and driving willingness.

Why This Research Matters

People who use alcohol and cannabis together are at higher crash risk, yet this study suggests they may actually feel more willing to drive — a dangerous mismatch between impairment and risk perception.

The Bigger Picture

As cannabis legalization expands, simultaneous use with alcohol is increasing. Understanding how this combination affects driving decisions — not just driving ability — is critical for public safety messaging.

What This Study Doesn't Tell Us

Self-selected sample of regular co-users may not represent broader population. Self-reported willingness to drive differs from actual driving behavior. Predominantly White sample (85.2%) limits diversity.

Questions This Raises

  • ?Does cannabis create a false sense of sobriety when combined with alcohol?
  • ?Should impaired driving campaigns specifically address simultaneous use scenarios?

Trust & Context

Key Stat:
Evidence Grade:
Innovative real-time EMA methodology capturing in-the-moment decisions, though limited by self-report and specific population.
Study Age:
Recent study using ecological momentary assessment to capture real-world driving decisions during substance use.
Original Title:
Event-level influences of alcohol, cannabis, and simultaneous use on perceived driving risk.
Published In:
Experimental and clinical psychopharmacology, 33(2), 170-177 (2025)
Database ID:
RTHC-07980

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Watches what happens naturally without intervening.

What do these levels mean? →

Frequently Asked Questions

Is it more dangerous to drive after using both alcohol and cannabis?

Yes — lab studies show simultaneous use impairs driving more than either substance alone. This study adds that people may paradoxically feel more willing to drive despite greater impairment.

Why would cannabis make people more willing to drive after drinking?

The authors suggest cannabis may attenuate alcohol's subjective effects on driving decision-making, creating a dangerous disconnect between actual impairment and perceived ability to drive.

Read More on RethinkTHC

Cite This Study

RTHC-07980·https://rethinkthc.com/research/RTHC-07980

APA

Wycoff, Andrea M; Darmour, Charles A; McCarthy, Denis M; Trull, Timothy J. (2025). Event-level influences of alcohol, cannabis, and simultaneous use on perceived driving risk.. Experimental and clinical psychopharmacology, 33(2), 170-177. https://doi.org/10.1037/pha0000758

MLA

Wycoff, Andrea M, et al. "Event-level influences of alcohol, cannabis, and simultaneous use on perceived driving risk.." Experimental and clinical psychopharmacology, 2025. https://doi.org/10.1037/pha0000758

RethinkTHC

RethinkTHC Research Database. "Event-level influences of alcohol, cannabis, and simultaneou..." RTHC-07980. Retrieved from https://rethinkthc.com/research/wycoff-2025-eventlevel-influences-of-alcohol

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkTHC research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.