Cannabis Workplace Research

Employment, drug testing, impairment at work

31 peer-reviewed studies

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RTHC-08474StrongSystematic Review

Urinary Δ9-tetrahydrocannabinol and metabolite concentrations following cannabis use: A systematic review.

McCartney, Danielle · 2026

This systematic review synthesized 92 studies examining urinary THC and THC-metabolite concentrations across different cannabis use patterns and testing contexts. The findings exposed major problems with current testing thresholds.

RTHC-06444StrongReview

Cannabis.

Feinberg, Steven D · 2025

Some evidence for MS spasticity, but no quality evidence for back pain, radiculopathy, neuropathic pain, or other common work-related pain.

RTHC-07874Strongclinical-trial

The Acute and Chronic Pharmacokinetic Oral Fluid Profile of Oral Cannabidiol (CBD) With and Without Low Doses of Delta-9-Tetrahydrocannabinol (Δ9-THC) in Healthy Human Volunteers.

Vikingsson, Svante · 2025

After taking 100 mg CBD with just 0.5 mg THC (well within legal hemp limits), 1 in 10 participants tested positive for THC in oral fluid.

RTHC-05832StrongCross-Sectional

Cannabis Use, Use Disorder, and Workplace Absenteeism in the U.S., 2021-2022.

Yang, Kevin H · 2024

Past-month cannabis use was associated with more missed work days due to illness and more skipped work days compared to no lifetime use.

RTHC-08225ModerateCross-Sectional

Illicit cannabis use among workers in Australia: A nationally representative cross-sectional analysis of prevalence, determinants, and associated absenteeism.

Di Censo, Gianluca · 2026

Weekly cannabis use was reported by 5.0% of workers.

RTHC-06652ModerateCross-Sectional

Workplace Drug Testing-Prevalence of Positive Test Results, Most Common Substances, and Importance of Medical Review.

Helander, Anders · 2025

This analysis of 23,900 workplace drug test results from Sweden provides a snapshot of substance use among employed people.

RTHC-06868ModerateCross-Sectional

Cross-sectional analysis of cannabis use at work in the USA: differences by occupational risk level and state-level cannabis laws.

Kucera, Ava · 2025

Workplace use highest in recreational states (8.5%) vs.

RTHC-07272ModerateCross-Sectional

Substance Use Right Before or During Work Among the Young US Workers: Evidence From the National Longitudinal Survey of Youth 1997 Cohort.

Oh, Sehun · 2025

8.9% of workers reported past-month substance use at work: 5.9% alcohol, 3.1% marijuana, 0.8% cocaine/hard drugs.

RTHC-04450ModerateLongitudinal Cohort

Workplace and non-workplace cannabis use and the risk of workplace injury: Findings from a longitudinal study of Canadian workers.

Carnide, Nancy · 2023

Among 2,745 Canadian workers followed from 2018-2020, workplace cannabis use (before or at work) was associated with a nearly two-fold increased risk of workplace injury (RR 1.97, 95% CI 1.32-2.93).

RTHC-04820Moderatescoping-review

Medicinal Cannabis and Implications for Workplace Health and Safety: Scoping Review of Systematic Reviews.

O'Neill, Veronica · 2023

Across 31 systematic reviews and meta-analyses, the most predominant adverse events of medical cannabis were sedation, nausea/vomiting, dizziness, and euphoria.

RTHC-05003ModerateObservational

Prevalence of ∆8-tetrahydrocannabinol carboxylic acid in workplace drug testing.

Vikingsson, Svante · 2023

Delta-8 THC has gone from obscure cannabinoid to widespread consumer product almost overnight, and this study shows it's already creating a significant presence in workplace drug testing.

RTHC-03836ModerateObservational

Increasing prevalence of illicit drug use among employees at Swedish workplaces over a 25-year period.

Feltmann, Kristin · 2022

Over 25 years and hundreds of thousands of workplace urine samples from across Sweden, the proportion testing positive for illicit drugs quadrupled — from 1.3% in 1994 to 5.6% in 2019.

RTHC-04024ModerateReview

A Clinical Framework for Assessing Cannabis-Related Impairment Risk.

MacCallum, Caroline A · 2022

The framework provides clinicians with a structured approach to evaluate impairment-related factors in medical cannabis patients, including dosing, tolerance, timing, and individual risk factors.

RTHC-04218ModerateRCT

Urinary Excretion Profile of Cannabinoid Analytes Following Acute Administration of Oral and Vaporized Cannabis in Infrequent Cannabis Users.

Sholler, Dennis J · 2022

Using federal workplace drug-testing criteria (50 ng/mL screening, 15 ng/mL confirmation), urine specimens tested positive for THC-COOH in 97.6% of oral cannabis sessions versus 59.5% of vaporized sessions at active THC doses..

RTHC-03048ModerateCross-Sectional

Patterns and correlates of workplace and non-workplace cannabis use among Canadian workers before the legalization of non-medical cannabis.

Carnide, Nancy · 2021

In a survey of 1,651 Canadian workers conducted in June 2018 — just months before recreational legalization — a quarter of those reporting past-year cannabis use said they'd used before or at work.

RTHC-03638ModerateObservational

Detection of Drugs in Oral Fluid Samples Using a Commercially Available Collection Device: Agreement with Urine Testing and Evaluation of A and B Samples Obtained from Employees at Different Workplace Settings with Uncontrolled Sampling Procedures.

Zheng, Yufang · 2021

This study compared 113 paired oral fluid and urine samples collected from a treatment center, testing for cannabis, amphetamines, benzodiazepines, opiates/opioids, and cocaine.

RTHC-02912ModerateObservational

Occupational Exposure to Secondhand Cannabis Smoke Among Law Enforcement Officers Providing Security at Outdoor Concert Events.

Wiegand, Douglas M · 2020

THC was detected in personal air samples (53-480 ng/m3) and area samples (up to 330 ng/m3).

RTHC-02052ModerateCross-Sectional

Employment and Marijuana Use Among Washington State Adolescents Before and After Legalization of Retail Marijuana.

Graves, Janessa M · 2019

Between 2010 and 2016, marijuana use decreased among 8th and 10th graders regardless of work status.

RTHC-01814ModerateCross-Sectional

Comparing medical and recreational cannabis use among employees: associations with health and work-related outcomes.

Rineer, Jennifer R · 2018

While some differences in health and work outcomes were initially seen between medical, recreational, and mixed-use cannabis users, several disappeared after controlling for health-related factors.

RTHC-01228ModerateReview

Techniques and technologies for the bioanalysis of Sativex®, metabolites and related compounds.

Molnar, Anna · 2016

As medical cannabis products like Sativex become more widely prescribed, drug testing faces a growing challenge: how to distinguish legal medical use from illicit recreational use. This review systematically examined methods for detecting THC and CBD across four biological matrices: blood, urine, oral fluid, and hair.

RTHC-01018ModerateCross-Sectional

School and work status, drug-free workplace protections, and prescription drug misuse among Americans ages 15-25.

Miller, Ted · 2015

Researchers analyzed data from over 20,000 young adults in national surveys to examine how school status, employment, and workplace drug policies relate to prescription drug misuse. Being a student was protective against prescription misuse.

RTHC-00252ModerateObservational

Cannabis use, cognitive performance and mood in a sample of workers.

Wadsworth, E J K · 2006

Cannabis users and controls completed laboratory cognitive tests before and after work at the start and end of a working week, along with daily workplace performance diaries. Cannabis use was associated with lower alertness and slower response organization across testing sessions.

RTHC-08158PreliminaryObservational

State Initiatives to Promote Cannabis Industry Entrepreneurship Among Disproportionately Impacted Communities: A Multi-State Analysis.

Chakraborty, Rishika · 2026

This multi-state analysis examined social equity entrepreneurship initiatives across all 17 states with legal non-medical cannabis retail as of May 2025.

RTHC-06901Preliminarynarrative-review

Effective cannabis testing protocols for workplace safety in South Africa post legalisation: Navigating the new normal.

Laurens, J B · 2025

South Africa's legalization of private cannabis use created an immediate tension with workplace drug testing policies—particularly in safety-sensitive industries like mining, construction, and transport.

RTHC-07293Preliminaryretrospective-cohort

Work-Related Asthma in the Cannabis Industry: Findings From California, Massachusetts, Michigan, and Washington.

Pacheco, Michelle · 2025

Of 30 work-related asthma cases in the cannabis industry, 52% were new-onset asthma and 48% were work-aggravated asthma.

RTHC-03905Preliminarynarrative-review

Workplace Cannabis Policies: A Moving Target.

Hazle, Mia C · 2022

The legal landscape for workplace cannabis use is a mess.

RTHC-02618Preliminarynarrative-review

Cannabis and work: Need for more research.

Howard, John · 2020

This commentary from researchers at NIOSH (the federal workplace safety agency) identified a fundamental gap: cannabis legalization was reshaping the American workforce, but almost no research existed to guide workplace policy.

RTHC-00578Preliminaryretrospective-cohort

Impact of lowering confirmatory test cutoff value in pre-enlistment urine cannabinoids screening: about five years' experience in the French Gendarmerie.

Lecompte, Yannick · 2012

Researchers reviewed 986 confirmation analyses of positive cannabis screening tests from French Gendarmerie pre-enlistment examinations over 5 years (2005-2009).

RTHC-00615PreliminaryCross-Sectional

A snapshot of workplace drug testing in Italy.

Santoro, Paolo Emilio · 2012

Under Italian workplace safety law, workers in hazardous jobs must undergo mandatory drug testing.

RTHC-00283PreliminaryCross-Sectional

Workplace drug testing in a military organization: results and experiences from the testing program in the Finnish Defence Forces.

Meririnne, Esa · 2007

The Finnish Defence Forces conducted a drug testing program from 2002 to 2005, testing soldiers, civilian personnel, and military students.

RTHC-00114PreliminaryReview

Workplace drug testing in Europe.

Verstraete, A G · 2001

Workplace drug testing in Europe lacked the standardized infrastructure found in the United States.